ACTRN12610000522011已完成未知
A randomised, controlled crossover trial of the effect of high concentration oxygen on transcutaneous carbon dioxide tension in obese hospitalised patients.
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 48
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Prevention
入排标准
- 年龄范围
- 16 Years 至 o limit（—）
- 性别
- All
入选标准
- •1. Current internal medicine inpatient in Wellington Hospital; 2. Age >/= 16 years; 3. Body Mass Index (BMI) > 40kg/m2.
排除标准
- •1. Diagnosis of Chronic Obstructive Pulmonary Disease (COPD); 2. Ratio of Forced Expiratory Volume in one second to Forced Vital Capacity (FEV1:FVC) < 0.7 (First 24 participants recruited only); 3. Patients currently receiving treatment with Continuous Positive Airway Pressure (CPAP) ventilation or Non-Invasive Positive Pressure Ventilation (NIPPV); 4. Patients currently requiring >2L/minute of oxygen therapy following titration to the recommended target saturation range of 88-92% (First 24 participants recruited only); 5. Patients with baseline PtCO2 of >65mmHg; 6. Current diagnosis of disease causing restriction to chest wall expansion, other than obesity i.e. neuromuscular disease or chest wall dysfunction; 7. Administration of respiratory suppressant medications, including opiate analgesia and benzodiazepines within 24 hours (First 24 participants recruited only); 8. Patients with unstable angina or recent myocardial infarction.
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