Effect of Smoking Cessation on Non-surgical Periodontal Therapy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 177
- 主要终点
- Change in Clinical Attachment Level (millimeters) after 24 months
研究概览
简要总结
The aim of this prospective study is to verify the efficacy of smoking cessation on non-surgical periodontal therapy in adult subjects with chronic periodontitis.
Smokers that were willing to quit received periodontal treatment and concurrent smoking cessation therapy. Periodontal maintenance was performed every 3 months. A calibrated examiner, blinded to smoking status, assessed periodontal status, gathered demographic and behavioural information with a structured questionnaire and measured air carbon monoxide concentration measurements.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •subjects were willing to stop smoking
- •>10 teeth
- •periodontitis (30% or more of their teeth with proximal CAL ≥ 5 mm
排除标准
- •systemic conditions considered as risk factors for periodontal disease,
- •periodontal therapy in the last 6 months
- •continuous systemic use of anti-inflammatory or steroidal drugs
研究组 & 干预措施
Adjunctive smoking cessation
non-surgical periodontal therapy and concurrent smoking cessation therapy
干预措施: Smoking cessation therapy (Behavioral)
Adjunctive smoking cessation
non-surgical periodontal therapy and concurrent smoking cessation therapy
干预措施: Non-surgical periodontal therapy (Procedure)
结局指标
主要结局
Change in Clinical Attachment Level (millimeters) after 24 months
时间窗: baseline and 24 months
次要结局
- Change in Gingival recession (millimeters) after 24 months(baseline and 24 months)
- Change in Pocket depth (millimeters) after 24 months(baseline and 24 months)
- Change in bleeding on probing (percentage of sites with bleeding) after 24 months(baseline and 24 months)
- Change in visible plaque (percentage of sites with visible plaque) after 24 months(baseline and 24 months)
研究者
Claudio Mendes Pannuti
Associate Professor
University of Sao Paulo