NCT00727051撤回不适用
Comparison of Coronary CT Angiography With Conventional Coronary Angiography in Liver and Lung Transplant Candidates.
适应症
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 1
- 主要终点
- patients suspected of having coronary artery disease (CAD)
研究概览
简要总结
The overall goal of this study is to determine if non-invasive imaging with state of the art CT coronary angiography can be used to screen for coronary artery disease in high risk patients prior to liver and lung transplantation. The current protocol for coronary artery disease assessment at UCSF before liver and lung transplantation involves screening with stress tests and/or coronary angiograms in patients with increased risk of coronary artery disease. Coronary angiogram will be used as gold standard for assessment of coronary CTA accuracy.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Liver transplant candidates referred for invasive coronary angiography which include:
- •Patients with suspicious symptoms for CAD or;
- •Asymptomatic patients;
- •Abnormal non-invasive testing or 1 major risk factor for coronary artery disease or LVEF < 60% on echo.
- •Lung transplant candidates referred for invasive coronary angiography which include:
- •Patients with suspicious symptoms for CAD or;
- •Asymptomatic patients;
- •Abnormal non-invasive testing or 1 major risk factor for coronary artery disease or LVEF < 60% on echo in patients with low SVR (typical for ESLD).
- •Any ethnic background is acceptable.
排除标准
- •Patients with contraindications for the use of iodinated contrast (allergic reaction, renal failure, multiple myeloma, etc) will be excluded.
- •Children and pregnant women will be excluded because of risks associated with radiation exposure.
- •Patients must have no atrial fibrillation, as this will interfere with cardiac gating for the examination.
- •Patients unable to give informed consent will be excluded as well.
结局指标
主要结局
patients suspected of having coronary artery disease (CAD)
时间窗: 1-30 days before invasive coronary angiography is performed
次要结局
未报告次要终点
研究者
研究点 (1)
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