Randomized Study of Intraoperative Glucose Saline Versus Ringer Lactatein Cancer Pediatric Patients Doing Major Surgeries and Impact on Electrolytes ,Glucose and pH
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- PH and lactate level
研究概览
简要总结
To compare two electrolytes maintenance in perioperative period in children undergoing major surgeries on perioperative change in pH,lactate,sodium and glucose level
详细描述
Patients were randomized into 2 groups ringer lactate versus 5%dextrose in 0.9% saline,using a computer generated random list in blocks of 4 after recruitment the enrolling investigators opened sealed opaque envelopes that concealed group allocation participants ,trial investigators,attending anesthetist providing general anesthesia for the cases and the outcomes were blinded to group allocation
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 1 Year 至 10 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •1to 10 years Children undergoing major surgeries ie considered major if any invasive procedure in which extensive resection will be preformed e.g body cavity is opened,organs are removed and normal anatomy is altered abd duration not less than 2 hours or more than 5 hours.
排除标准
- •patient guardian refusal
- •_ Children with documented endocrine distrubances(DM,inborn error of metabolism,hyperthyroidism)
- •age less than one year
- •preexisting renal disease,hepatic disease and patien suffering from heart failure.
- •preexisting electrolyte imbalance (normal sodium level 135-145)
结局指标
主要结局
PH and lactate level
时间窗: In the introperative period
Three ABG will be collected from the patient. The first at start before any intervention,the second after start of replacement and the third at the end of the operation.
次要结局
- Sodium and glucose level(The intraoperative period)
研究者
Mona Mohammed Atteya
Anesthesia specialist
National Cancer Institute, Egypt