RBR-82zbbb2进行中（未招募）未知
Brain Connectivity and Neuroprogression. Multimodal MRI approach in victims of sexual abuse (adolescents and adults) with Post Traumatic Stress Disorder
niversidade Federal de São Paulo0 个研究点开始时间: 2021年12月8日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 进行中（未招募）
- 发起方
研究概览
简要总结
To evaluate the structural, functional and metabolic changes in the brain in PTSD ( post traumatic stress disorder ), in a population of adolescents victims of sexual violence, using different modalities of Magnetic Resonance imaging (Structural, Functional, Spectroscopy and DTI-diffusion tensor imaging). Evaluate the effect of therapeutic interventions - interpersonal therapy s and sandpaly and on brain structure, functioning and metabolism.
研究设计
- 研究类型
- Intervention
入排标准
- 年龄范围
- 14Y 至 17Y（—）
- 性别
- Female
入选标准
- •Case: have been victims of sexual violence; age between 14 and 17 years; to have Post traumatic stress disorder (PTSD) diagnosis after the application of the Clinician administered PTSD scale for children and adolescents (CAPS CA) performed in the screening; parents must be able to understand the informed consent term and the patient to understand, consent and sign the consent form for participation in the research; absence of intellectual deficit. Controls: did not present psychiatric diagnoses through the scale Schedule for Affective Disorders and Schizophrenia for School-Aged Children (K-SADS) , did not have a traumatic event of sexual violence through the CAPS-CA scale; do not present a history of cranial trauma with diagnosed brain injury, treatment of epilepsy or neurosurgery; do not present decompensated clinical diseases that require intensive treatment; do not present significant intellectual deficits; absence of use of psychoactive substances in the last 6 months; not being pregnant; parents must be able to understand the informed consent term and the patient to understand, consent and sign the consent form for participation in the research; absence of intellectual deficits , intelligence coeficient( IQ)below 70.
排除标准
- •Case: present psychiatric diagnoses prior to the traumatic event of sexual violence; present a history of cranial trauma with diagnosed brain injury, treatment of epilepsy or neurosurgery; presenting with decompensated clinical diseases that require intensive treatment; present significant intellectual deficits; have a diagnosis of psychoactive substance dependence in the last 6 months; Pregnancy detected through blood test.Controls: present psychiatric diagnoses; present a history of cranial trauma with diagnosed brain injury, treatment of epilepsy or neurosurgery; presenting with decompensated clinical diseases that require intensive treatment; present significant intellectual deficits; have a diagnosis of psychoactive substance dependence in the last 6 months; pregnancy detected through blood test; have been sexually abused.
研究者
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