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临床试验/NCT06630754
NCT06630754尚未招募不适用

An Exploration of Body Composition in Older Adults Undergoing Systemic Anticancer Treatment.

Royal Marsden NHS Foundation Trust1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2024年11月1日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
30
试验地点
1
主要终点
Explore body composition in older adults with cancer starting SACT.

研究概览

简要总结

The primary aim of the study is to explore body composition in older adults (aged 70 years and over) with cancer, undergoing systemic anticancer treatment. Additional aims include to explore the extent of body composition changes and whether changes are tumour specific, the incidence for cancer-related cachexia and sarcopenia and finally, how body composition can inform nutritional management of older adults with cancer.

To do this, the investigators applied for and were awarded funding from a company called Nutricia to pay for a band 4 (0.6 WTE for 7 months) to take monthly body composition measures on the patients who are eligible, accepting of assessment by the Senior Adult Oncology Programme (SAOP) and consent to these measures. Measurements will include an analysis from the Bioelectrical Impedance Analysis (BIA) machine which will quantify fat, lean muscle, and water content; waist to hip ratio; handgrip strength; calf circumferences. Socio-demographic data will also be collected.

Descriptive data analysis will take place to explore possible trends and associations which may inform future research and drive even further personalised care for this growing and typically underrepresented in research, population.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
70 Years 至 —(Older Adult)
性别
All
接受健康志愿者

入选标准

  • Adults eligible and accepting of assessment in the SAOP.
  • adults aged 70 years and over
  • a cancer diagnosis
  • just starting SACT
  • able to provide at least 2 data sets during the study period (baseline + at least 1 research clinic visit)
  • willing and able to provide written informed consent

排除标准

  • No further exclusions

结局指标

主要结局

Explore body composition in older adults with cancer starting SACT.

时间窗: 7 months

means and standard deviations (or medians and interquartile ranges if not normally distributed) of body composition measures taken from all participants at baseline/ first Research Clinic, analysed at end of study will quantify this objective.

次要结局

  • Explore the extent of body composition changes in older adults with cancer during SACT.(7 months)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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