The Effect of Transcutaneous Auricular Vagal Nerve Stimulation (taVNS) on Pupillary Response and Perceptual Learning
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 12
- 试验地点
- 2
- 主要终点
- Change in Time It Takes to Reach 90% of Asymptotic Level Performance
研究概览
简要总结
This study has two parts. The study team will evaluate transcutaneous auricular vagal nerve stimulation (taVNS) and two sham settings during a passive task while measuring pupillary response. Second, the study team will assign either taVNS, sham, or no intervention during a go/no-go task and evaluate perceptual learning over three sessions which will also include measuring the pupillary response and electroencephalogram (EEG).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy individuals 18 to 65
- •Normal audiometric testing
排除标准
- •Co-morbidities including cardiomyopathies, arrhythmias
- •Implantable devices including vagal stimulators, pacemakers
- •Presence of metallic implants
- •Pregnancy
结局指标
主要结局
Change in Time It Takes to Reach 90% of Asymptotic Level Performance
时间窗: Baseline, Month 3
Will be measured during performance on a go/no-go task.
Change in Speed of Learning to Perform a Behavioral Task
时间窗: Baseline, Month 3
Will be measured during performance on a go/no-go task.
Change in Overall Mean Peak (Pupillary Response)
时间窗: Baseline, Month 3
Pupillary responses will be measured noninvasively using a video camera during a go/no-go task.
次要结局
未报告次要终点