Burden of Illness and Disease Associated Emergencies in Chronic Hypoparathyroidism
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 205
- 试验地点
- 5
- 主要终点
- Burden of illness
研究概览
简要总结
Long-term conventional treatment of chronic hypoparathyroidism does not fully restore calcium homeostasis leading to increased morbidity, emergency events and reduced subjective health status. To further investigate general morbidity, hypocalcemic events, subjective and daily life performance in patients with chronic hypoparathyroidism a disease specific questionnaire, as well as the SF-36 are handed out.
详细描述
Design:
In a cross-sectional trial the subjective health status and burden of illness in patients with chronic hypoparathyroidism will be evaluated by using a disease specific questionnaire as well as the SF-36.
Patients:
Patients will be recruited out of the patient population of the participating five medical centers.
Statistical Analysis:
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •chronic hypoparathyroidism (>12 months) under established therapy
- •chronic pseudohypoparathyroidism (>12 months) under established therapy
- •written informed consent
排除标准
- •age <18 years
- •no detailed documentation of hypo- or pseudohypoparathyroidism
结局指标
主要结局
Burden of illness
时间窗: 12 - 24 months
Assessment of the burden of illness due to chronic hypoparathyroidism using a disease specific questionnaire to further investigate impairment in daily and professional life in comparison to the general German population (DEGS1, SHIP-2).
次要结局
- Subjective Health Status(12-24 months)
- Psychological disorders(12 - 24 months)
- Hypocalcemia(12 - 24 months)
研究者
Stefanie Hahner
Prof. Stefanie Hahner
University of Wuerzburg