NCT01984957已完成不适用
Differential Study of Muscle Transcriptome in Patients With Neuromuscular Disease and Control Subjects
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 42
- 试验地点
- 2
- 主要终点
- Gene expression levels
研究概览
简要总结
To isolate biomarkers of ALS in muscle
详细描述
At present, there is no validated biological diagnostic marker for amyotrophic lateral sclerosis (ALS). The main objective of the study is to isolate a set of genes that are specifically dysregulated in muscle from ALS patients.
Gene profiling in muscle will be compared between ALS patients and patients with other motor neuron diseases (SMA and SBMA)
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Gene expression levels
时间窗: day 1
Gene expression levels in muscle as determined By microarrays (transcriptome analysis)
次要结局
- muscle denervation(day 1)
- Functional evaluation(day 1)
研究者
研究点 (2)
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