A Comparison of Cognitive Training Approaches in Psychotic Disorders
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 70
- 试验地点
- 2
- 主要终点
- Change in Functional Performance - Specific Levels of Functioning (SLOF) from Baseline
研究概览
简要总结
Cognitive remediation (CR) is the best treatment to improve neurocognitive abilities for individuals with psychosis, however, there is no gold standard method of cognitive remediation available. Cognitive training refers to the training component of CR in which people practice computerized exercises that train specific cognitive abilities. There is no agreed upon approach within the field as to the type of training that is most effective with some studies, training higher level cognitive abilities, some training perceptual abilities, and others training general cognitive skills. This study will directly compare two competing methods of cognitive training on measures of neurophysiology, neurocognition, functional competence, and real-world functional performance.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •psychotic disorder
- •No previous cognitive remediation in past 6 months
排除标准
- •Brain injury
- •Substance abuse
- •Neurocognitive disorder
- •Developmental Disability
研究组 & 干预措施
Executive Training
Executive Training (ET) involves training on computerized cognitive exercises that have graded increases in difficulty so that the participant is always challenged. A therapist will be in the room with participants to address any difficulties with the program and facilitate generation of strategies. ET will be delivered in both individual and group settings.
干预措施: Cognitive Remediation - Executive Training (Behavioral)
Perceptual Training
Perceptual Training (PT) involves training on computerized cognitive exercises that have graded increases in difficulty so that the participant is always challenged. A therapist will be in the room with participants to address any difficulties with the program and facilitate generation of strategies. PT will be delivered in both individual and group settings.
干预措施: Cognitive Remediation - Perceptual Training (Behavioral)
结局指标
主要结局
Change in Functional Performance - Specific Levels of Functioning (SLOF) from Baseline
时间窗: Post-treatment (within 2 weeks following the end of treatment)
Rating scale completed by participants' case managers that rates their ability to perform different everyday tasks
次要结局
- Change in Neurocognition - MATRICS Cognitive Consensus Battery (MCCB) from Baseline(Follow-Up (3 months after the end of treatment))
- Change in Neurophysiology - EEG from Baseline(Follow-Up (3 months after the end of treatment))
- Functional Competence - Canadian Objective Assessment of Life Skills Brief (COALS-B) from Baseline(Follow-Up (3 months after the end of treatment))
- Change in Functional Performance - Specific Levels of Functioning (SLOF) from Baseline(Follow-Up (3 months after the end of treatment))
研究者
Dr. Christopher Bowie
Principal Investigator
Queen's University