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临床试验/NCT00760357
NCT00760357已完成不适用

A Retrospective Analysis of Patients With Full Thickness Wounds in Limbs With Critical Ischemia

Southwest Regional Wound Care Center1 个研究点 分布在 1 个国家目标入组 190 人开始时间: 2007年4月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
190
试验地点
1
主要终点
Once the patients are identified that have a full thickness wound on a limb clearly identified as having critical limb ischemia, these patients will be evaluated

研究概览

简要总结

Once the patients are identified that have a full thickness wound on a limb clearly identified as having critical limb ischemia, these patients will be evaluated. The data that will be extracted from each chart will include patient's age, patient's gender, number of office visits, presence of diabetes, presence of osteomyelitis, type and amount of antibiotic administered, number of hyperbaric oxygen treatments, and if the wound healed.

详细描述

Clinicians have even learned to group patients into different etiologic categories based on underlying disease such as diabetes mellitus, decubitus ulcer, surgical site infection, venous insufficiency, arterial insufficiency and others. It seems that wounds have been grouped into these categories because of their common barriers, which should allow us more precise algorithms and may provide better outcomes. That is diabetics tend to have the barriers of poor perfusion, endothelial cell dysfunction, white blood cell dysfunction, hyperglycemia, neuropathy and repetitive trauma. Venous insufficiency patients tend to have perivascular cuffing and peri wound edema. However patients with venous leg ulcers commonly have peripheral arterial disease and diabetes (3). The point is regardless of the etiology of the wound every patient must be evaluated for all barriers on every visit. Arbitrarily dividing chronic wounds in the etiologic categories has not significantly improved wound healing outcomes.

研究设计

研究类型
Observational
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • The inclusion criteria for the study are patients that demonstrate the following:
  • A limb with a TCpO2 less than 20 with a full thickness wound.
  • Initial visit from August 1, 2002 to December 31, 2005.

排除标准

  • The exclusion criteria for the study are patients that demonstrate the following:
  • Partial thickness wound or no wound in limb with critical ischemia.
  • A medical record that does not clearly demonstrate critical limb ischemia or does not clearly demonstrates a full thickness wound.

结局指标

主要结局

Once the patients are identified that have a full thickness wound on a limb clearly identified as having critical limb ischemia, these patients will be evaluated

时间窗: 1 year

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Randall Wolcott

Principal Investigator

Southwest Regional Wound Care Center

研究点 (1)

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