临床试验/NCT00999973

NCT00999973Unknown1 期

Study on the Effect of Mitomycin C 0.02% on the Corneal Endothelial After Photorefractive Keratectomy in Moderate Myopia

Shahid Beheshti University of Medical Sciences1 个研究点分布在 1 个国家开始时间: 2009年9月最近更新: 2009年10月22日

适应症

干预措施

试验速览

阶段: 1 期
发起方: Shahid Beheshti University of Medical Sciences
试验地点: 1

研究概览入排标准研究组 & 干预措施研究者研究点记录与标识符相似试验

研究概览

简要总结

In this study 126 eyes in 63 patients with moderate bilateral myopia and astigmatism between -3 and -5 (SE difference between two eyes should not be more than 0.75 and the residual corneal thickness>350 μ ) were entered in the study. One eye went randomly under PRK with mitomycin C 0.02% in 15 min and then the other eye went under the operation without MMC. UCVA,BCVA, refractory error after the operation and the number of endothelial cells before and after the surgery would be compared in 6 months.

研究设计

研究类型: Interventional

入排标准

年龄范围: 19 Years 至 60 Years（Adult）
性别: All
接受健康志愿者: 否

入选标准

•19 < age < 60
•Refractory error stabled for at least one year
•No corneal pathology
•-3 < bilateral myopia and astigmatism < -5 with no difference more than 0.75 between 2 eyes
•Exclusion criteria:
•Keratoconus
•Ectatic corneal disease
•Corneal dystrophy
•Lens changes affecting the visual acuity
•Anterior or posterior uveitis
•Corneal scar

排除标准

未提供

研究组 & 干预措施

Mitomycin c 0.02%

Active Comparator

干预措施: Mitomycin C 0.02% (Drug)

Placebo

Placebo Comparator

干预措施: Placebo (Drug)

研究者

发起方

Shahid Beheshti University of Medical Sciences

申办方类型

Other

研究点 (1)

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