Efficacy of Iodine Complex in Mild to Moderate COVID-19 Patients
试验速览
- 阶段
- 1 期
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- HRCT chest
研究概览
简要总结
The objective of this study is to measure the effect of Iodine complex in treating the COVID-19 patients to clear viral load of SARS-CoV-2 along with reduction in severity of symptoms and length of hospitalization of patients with COVID-19.
详细描述
The proposed study is a placebo-controlled, add-on, randomized trial using parallel group designs. This is a close-label and adaptive, multi-centered design with 1:1:1:1 allocation ratio and superiority framework.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
盲法说明
empty capsule will be given as a placebo
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Positive PCR with mild to moderate disease
排除标准
- •Allergic to iodine
- •Any co-morbidity other than hypertension and dietetics
研究组 & 干预措施
Iodine Complex (Capsule form)
Iodine Complex) capsule (200mg) will be given three times a day
干预措施: Iodine Complex (Drug)
Iodine Complex (Syrup form)
Iodine Complex syrup form (40ml) will be given three times a day
干预措施: Iodine Complex (Drug)
Standard Care Alone
Placebo as empty capsule. Treatment will be given for all 4 arms will be receiving standard care as per version 3.0 of clinical management guidelines for COVID-19 established by the Ministry of National Health Services of Pakistan COVID-19 guidelines of the study setting.
干预措施: Placebo (Drug)
Iodine Complex (Nasal Spray)
Iodine complex throat spray of 2 puffs three times a day.
干预措施: Idoine Complex (Drug)
结局指标
主要结局
HRCT chest
时间窗: 14 days
Time taken for radiological improvement
qRT-PCR
时间窗: 14 days
Time taken for viral load clearance
次要结局
- Severity of Symptoms(14 days)
研究者
Sohaib Ashraf
Post-Graduate Resident Cardiology
Sheikh Zayed Federal Postgraduate Medical Institute