Evaluation Of Combined Efficacy Of Photodynamic Therapy and non-surgical periodontal therapy on Clinical and Microbial parameters in the management of chronic periodontitis subjects; Randomized Controlled Clinical Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 33
- 试验地点
- 1
- 主要终点
- clinical parameters:
研究概览
简要总结
Title: Evaluation of Combined Efficacy of Photodynamic Therapy and Non-Surgical Periodontal Therapy On Clinical and Microbial Parameters In The Management Of Chronic Periodontitis Subjects-Randomized Controlled Clinical Trial
In this observational study we propose to assess the improvement in clinical and microbial parameters after multiple application of Photodynamic Therapy (PDT) using Indocyanine Green (ICG) and Diode Laser (810 nm) as an adjunct to non- surgical periodontal therapy in moderate periodontal pockets for a period of 6 months. If the multiple application of PDT is proven to be effective it can be recommended as a regular treatment protocol in order to avoid invasive surgical procedures.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Open Label
入排标准
- 年龄范围
- 35.00 Year(s) 至 44.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients Aged
- •44 years 2)AAP 1999 criteria will be followed for diagnosis of chronic periodontitis patients 3)Patient having with bilateral periodontal destruction in mandibular posterior segment (involving minimum 3 teeth). 4)Periodontal destruction manifesting in form of moderate periodontal pockets (5-6mm) with clinical attachment loss.
排除标准
- •Smokers 2)Pregnancy or use of hormone contraceptives 3)Systemic condition / disease/ any medication having influence on the course of periodontal disease and therapy 4)Patients with history of use of antibiotics within the last 6 months and use of anti-inflammatory drugs within the last 3 months 5)Patients with history of periodontal treatment in the last year 6)Sites with gingival recession / pseudo periodontal pockets / advanced periodontal destruction with intra bony defects/ mobility 7)Teeth with restorations, endodontic lesions 8)Patients who are known hypersensitive for PDT dye 9)Patients contraindicated for laser intervention.
结局指标
主要结局
clinical parameters:
时间窗: baseline, 3 months, 6months
1.Probing Pocket Depth
时间窗: baseline, 3 months, 6months
2.Clinical Attachment Loss
时间窗: baseline, 3 months, 6months
次要结局
- Microflora in subgingival plaque samples(Baseline and 6 months)