Factors Affecting Treatment Response in Patients With Medication-Overuse Headache Undergoing Greater Occipital Nerve Blockade
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 70
- 试验地点
- 2
- 主要终点
- the number of days of analgesic use for headache
研究概览
简要总结
The aim of this study to evaluate pre-injection patient-related factors that may influence treatment response in patients with medication-overuse headache who underwent ultrasound-guided greater occipital nerve block.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age between 18 and 65 years
- •Diagnosis of medication-overuse headache according to the International Classification of Headache Disorders, 3rd edition (ICHD-3)
- •Diagnosis of medication-overuse headache associated with the use of triptans or nonsteroidal anti-inflammatory drugs
- •Previous diagnosis of chronic migraine or chronic tension-type headache according to the ICHD-3 criteria
排除标准
- •History of severe head or neck trauma or previous neurosurgical intervention
- •Presence of a severe psychiatric disorder (e.g., severe depression, schizophrenia)
- •History of infectious disease, chronic inflammatory disease, or malignancy
- •Previous diagnosis of secondary headache
- •History of substance abuse
- •Pregnancy or breastfeeding
- •History of an additional neurological disorder (e.g., cerebrovascular disease, multiple sclerosis)
- •Difficulty with cooperation
- •Presence of a concomitant systemic disease that may affect quality of life (e.g., congestive heart failure, chronic kidney disease, chronic liver disease, pulmonary disease, uncontrolled diabetes, or peripheral vascular disease)
研究组 & 干预措施
Treatment success group
Patients who demonstrated a ≥50% reduction in the number of days of analgesic use for headache at the end of the second-month evaluation
干预措施: Treatment outcome (Other)
Treatment failure group
Patients who demonstrated a <50% reduction in the number of days of analgesic use for headache at the end of the second-month evaluation
干预措施: Treatment outcome (Other)
结局指标
主要结局
the number of days of analgesic use for headache
时间窗: Baseline
Patients will be questioned the total number of days on which they used analgesics for headache during the past month.
次要结局
- Headache severity(Baseline)
- Post-injection pain severity(Baseline)
- Headache-related disability(Baseline)
- Pressure pain threshold(Baseline)
- Anxiety and depression levels(Baseline)
- Sleep quality(Baseline)
研究者
Alper Mengi
Associate Professor
Sultan 1. Murat State Hospital