Reduction of Length of Stay by Automated Adjustment of Oxygen on Patient With Acute COPD Exacerbation - FreeO2 HypHop
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 17
- 试验地点
- 2
- 主要终点
- Hospital length of stay
研究概览
简要总结
The aim of this study is to evaluate if automated adjustment of oxygen (with FreeO2 device) can reduce the hospital length of stay for acute exacerbation of COPD with comparison of manual oxygen titration.
详细描述
The aim of this study is to evaluate if automated adjustment of oxygen (with FreeO2 device) can reduce the hospital length of stay for acute exacerbation of COPD with comparison of manual oxygen titration.
Patients with severe acute exacerbation of COPD requiring hospitalization will be included in this randomized controlled study and will be managed with either manual oxygen titration or automated oxygen titration (FreeO2 arm).
The impact on the hospital length of stay will be evaluated.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •COPD or suspected COPD ( Age>40, active or smoking history > 10pack/years), -
- •Acute exacerbation (increasing dyspnea recently)
- •One or more of the following criteria: increased sputum, modification of sputum purulence,increased dyspnea,
- •Moderate oxygen therapy: Oxygen flow < 8 lpm (or FiO2 < 0.60) to maintain a SpO2 >or = 92% (for long term oxygen therapy, the oxygen flow must be greater than baseline flow to maintain SpO2 > or = 92%)
排除标准
- •Patient refusal
- •COPD exacerbation with diagnosis highly related to pulmonary embolism, cardiac pulmonary edema, pneumothorax or sedative overdose
- •No SpO2 signal
- •Encephalopathy score > 2
- •Other respiratory support needed (intubation or NIV)
- •Patient on withdrawal life support
- •Advance neoplasia (palliative stage) or terminal respiratory distress
- •Unavailability of FreeO2 device at the randomisation
- •Non optimal patient collaboration
结局指标
主要结局
Hospital length of stay
时间窗: From hospital admission until hospital discharge (around one week expected)
Duration of the hospital length of stay
次要结局
- Non invasive or invasive mechanic ventilation rate use(During hospital stay: from hospital admission until hospital discharge (around one week expected))
- ICU transfer(During hospital stay : from hospital admission until hospital discharge (around one week expected))
- Oxygen administration duration(During hospital stay : from hospital admission until hospital discharge (around one week expected))
研究者
François Lellouche
Principal Investigator
Laval University