A study to compare the safety and efficacy of two different strengths of transdermal buprenorphine for the treatment of post-operative pain following surgery for proximal femoral fracture
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 75
- 试验地点
- 1
- 主要终点
- Visual analogue scale (VAS)
研究概览
简要总结
I am conducting a study to compare the safety and efficacy of two different strengths of transdermal buprenorphine for the treatment of post-operative pain following surgery for proximal femoral fracture.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Not Applicable
入排标准
- 年龄范围
- 18.00 Year(s) 至 80.00 Year(s)（—）
- 性别
- All
入选标准
- •of patients- 75 ASA- I to III Patients undergoing surgery for proximal femoral fractures under spinal anesthesia.
排除标准
- •Patients having poly trauma with any other fracture, Obese, hepatic or renal impairment, myasthenia gravis, delirium tremens, skin allergy.
结局指标
主要结局
Visual analogue scale (VAS)
时间窗: Visual analogue scale (VAS) at 2 hrs,4 hrs,6 hrs,12 hrs,24 hrs,3rd day,5th day,7th day | Post operative nausea and vomiting(PONV) at 2 hrs,4 hrs,6 hrs 12 hrs,24 hrs,3rd day, 5th day 7th day | Rescue analgesia at 1st,2nd,3rd,4th,5th,6th,7th day | Complications at 1st,2nd,3rd,4th,5th,6th,7th day
Post operative nausea and vomiting(PONV)
时间窗: Visual analogue scale (VAS) at 2 hrs,4 hrs,6 hrs,12 hrs,24 hrs,3rd day,5th day,7th day | Post operative nausea and vomiting(PONV) at 2 hrs,4 hrs,6 hrs 12 hrs,24 hrs,3rd day, 5th day 7th day | Rescue analgesia at 1st,2nd,3rd,4th,5th,6th,7th day | Complications at 1st,2nd,3rd,4th,5th,6th,7th day
Rescue analgesia
时间窗: Visual analogue scale (VAS) at 2 hrs,4 hrs,6 hrs,12 hrs,24 hrs,3rd day,5th day,7th day | Post operative nausea and vomiting(PONV) at 2 hrs,4 hrs,6 hrs 12 hrs,24 hrs,3rd day, 5th day 7th day | Rescue analgesia at 1st,2nd,3rd,4th,5th,6th,7th day | Complications at 1st,2nd,3rd,4th,5th,6th,7th day
Complications
时间窗: Visual analogue scale (VAS) at 2 hrs,4 hrs,6 hrs,12 hrs,24 hrs,3rd day,5th day,7th day | Post operative nausea and vomiting(PONV) at 2 hrs,4 hrs,6 hrs 12 hrs,24 hrs,3rd day, 5th day 7th day | Rescue analgesia at 1st,2nd,3rd,4th,5th,6th,7th day | Complications at 1st,2nd,3rd,4th,5th,6th,7th day
次要结局
- Heart rate(Mean arterial pressure)