Evaluation of preoperative diagnostic imaging for adult endogenous hyperinsulinemic hypoglycaemia by PET imaging with 68Ga-NODAGA-exendin-4 compared to standard care imaging procedures - GLP-1-AHH

Hospital District of Southwest Finland, Turku University Hospital0 个研究点目标入组 56 人开始时间: 2017年5月23日最近更新: 2017年7月3日

适应症

试验速览

暂无简介。

•Biochemically proven endogenous hyperinsulinemic hypoglycemia: neuroglycopenic symptoms in the fasting state with low plasma glucose, inappropriately high serum insulin and C-peptide concentrations
•? Signed informed consent
•? Standard imaging not older than 8 weeks. This includes a triple-phase CT or MRI, somatostatin receptor imaging (68Ga-DOTATOC PET) and endocopic ultrasound (EUS). Protocols that should be followed for these procedures can be found in the annex.
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 9
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range 1

•Breast feeding
•? Pregnancy or the wish to become pregnant within 6 months
•? Calculated creatinine clearance below 40ml/min
•? Evidence of other malignancy than insulin producing tumors in conventional imaging (suspicious liver, bone and lung lesions)
•? Age < 18 years

发起方

Hospital District of Southwest Finland, Turku University Hospital