NCT01606865已完成不适用
Does Platelet Inhibition Predict Surgery Related Bleeding in Patients Undergoing Non-Cardiac Surgery During Dual Antiplatelet Therapy
Medical University of Graz1 个研究点 分布在 1 个国家目标入组 207 人开始时间: 2010年9月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 207
- 试验地点
- 1
- 主要终点
- increased risk of bleeding (according to TIMI definition)
研究概览
简要总结
The aim of the study is to evaluate if there is an association between platelet inhibition and surgery-related bleeding in patients undergoing non-cardiac surgery during dual antiplatelet therapy.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •intake of Clopidogrel, Prasugrel, or Ticagrelor within the last 7 days
- •spontaneous bleeding or impeding surgery (major vascular surgery, intraperitoneal or intrathoracic surgery, ENT-surgery, orthopedic or trauma surgery, prostatic surgery)
排除标准
- •concomitant medication with warfarin
- •renal insufficiency needing dialysis
- •concomitant therapy with GPIIB/IIIA Antagonists
- •expected duration of operation >30min
结局指标
主要结局
increased risk of bleeding (according to TIMI definition)
时间窗: 24hours postoperatively
次要结局
未报告次要终点
研究者
Helfried Metzler, MD
Prof.
Medical University of Graz
研究点 (1)
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