A Comparison of effect of preloading versus coloading on umbilical arterial pH in parturients undergoing elective cesarean section A randomized controlled trial
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Umbilical Arterial pH
研究概览
简要总结
This study will enroll parturients undergoing elective cesarean section under subarachinoid block randomly allocated into two groups, group P1 preloaded with 1oml/kg of body weight of crystalloids and group P2 coloaded with 10ml/kg of body weight of crystalloids . The umbilical arterial blood sample will be collected and hemodynamic parameters of the parturient will be recorded by an anaesthesiologist who will be blinded to whether the parturient was preloaded or coloaded. The umbilical arterial pH values and hemodynamic parameters of parturients will be compared between the two groups.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 35.00 Year(s)（—）
- 性别
- Female
入选标准
- •a)parturients willing to give informed consent b)ASA status II c)height measuring between 150-170cms d)elective cesarean sections done under subarachinoid block.
排除标准
- •a)any contraindications to subarachinoid block b)known hypersensitivity to local anaesthetics c)complicated pregnancies d)obesity e)inadequate subarachinoid block.
结局指标
主要结局
Umbilical Arterial pH
时间窗: Umbilical arterial blood sample collected immediately after delivery of the baby | APGAR scores recorded at 1min and 5mins after the birth of baby
APGAR scores
时间窗: Umbilical arterial blood sample collected immediately after delivery of the baby | APGAR scores recorded at 1min and 5mins after the birth of baby
次要结局
- hemodynamic parameters of the mother(hemodynamic parameters recorded from pre-operative period till the end of the surgery)
研究者
Dr Shreeba B V
Bangalore Medical College and Research Institute , RGUHS