Pilot study to investigate the anti-inflammatory effects of caffeine in subjects with chronic obstructive pulmonary disease (COPD) - Anti-inflammatory effects of caffeine in COPD

Technologiestichting STW (NWO)0 个研究点目标入组 12 人开始时间: 待定最近更新: 2024年5月13日

适应症

试验速览

暂无简介。

•Male subjects in an age of 40-70 years
•BMI > 20 kg/m2 and < 30 kg/m2
•Diastolic blood pressure (DBP)=60-90 mmHg, Systolic blood pressure (SBP)=100-150 mmHg
•CRP-levels > 3mg/l
•No acute and/or chronic inflammatory condition such as arthritis, arthrosis, chronic colitis, etc. during three months before entry of the study
•No respiratory tract infection or exacerbation of COPD for at least 8 weeks prior to the start of the study
•No change in treatment regime of the COPD subjects for at least 8 weeks prior to the start of the study
•Normal constant dietary eating habits and a usual coffee consumption of at least 3 cups per day
•Non-smokers and stopped smoking, respectively

•age < 40 years or > 70 years old
•BMI <= 20 kg/m2 and >= 30 kg/m2
•Diastolic blood pressure (DBP) < 60 or > 90 mmHg, systolic blood pressure (SBP) <100 or >150 mmHg
•Acute and/or chronic inflammatory condition such as arthritis, arthrosis, chronic colitis, etc. during three months before entry of the study
•Respiratory tract infection or exacerbation of COPD during the last 8 weeks prior to the start of the study
•Change in treatment regime of the COPD subjects during the last 8 weeks prior to the start of the study
•Irregular eating habits, usual coffee consumption of less than 3 cups per day and current smoker

发起方

Technologiestichting STW (NWO)