Association of Cardiac Biomarker Elevation After Marathon Running and Coronary Atherosclerosis - the MaraCat Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 43
- 试验地点
- 1
- 主要终点
- Association Cardiac troponin-T level and coronary CT findings
研究概览
简要总结
This study evaluates cardiac biomarkers and their association to coronary artery disease in marathon runners.
详细描述
The MaraCat study is an observational prospective study evaluating the association between cardiac biomarkers and coronary artery disease in 43 runners participating in the 2018 Paavo Nurmi Marathon. The study participants were recruited according to two age criteria - under 35 years and over 44 years of age. Comprehensive laboratory samples were collected immediately after the run, while the control workup was done in a separate visit with no significant physical excercise in the preceding two weeks. In the under 35 years -group, the control workup included an echocardiography, ecg and blood samples. In the over 44 years group, the control studies included coronary CT, echocardiography, ecg and laboratory tests.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 35 Years 至 90 Years（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Age under 35 years or over 44 years
- •Participant of Paavo Nurmi Marathon 2018
- •Informed consent signed
排除标准
- •No informed consent
- •existing coronary artery disease
结局指标
主要结局
Association Cardiac troponin-T level and coronary CT findings
时间窗: Cardiac Troponin-T 0-30 minutes after finishing the Paavo Nurmi Marathon. Control Troponin-T levels and coronary CT angiography at control visit (>30days after marathon).
Cardiac troponin-T levels (ng/L), \[electrochemiluminescence (ECLIA) method\]
Cardiac Troponin-T level after marathon
时间窗: 0-30minutes after finishing the Paavo Nurmi Marathon
Cardiac troponin-T levels (ng/L), \[electrochemiluminescence (ECLIA) method\]
次要结局
未报告次要终点
研究者
Juhani Airaksinen
Professor
Turku University Hospital