Qatar Universal Diabetes Outcomes (QUDOS) Study
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- 入组人数
- 475
- 试验地点
- 1
- 主要终点
- Diabetes Complications (Nephropathy, Neuropathy, Retinopathy)
研究概览
简要总结
QUDOS is a cross-sectional population study aiming to answer key questions about diabetes and its complications in Qatar as well as identify factors associated with the development and progression of diabetes complications.
详细描述
QUDOS aims to gain a better understanding of diabetes in primary and secondary care over a period of 24 months.
A range of patients with diabetes will be sampled (including those with Type 1 diabetes as this group is under-studied in Qatar). This will be important in designing appropriate intervention plans that will improve diabetic patients' health conditions to prevent or delay the onset of complications and will provide a strong foundation for longitudinal study.
The broad objectives of the study are:
QUDOS 1: Aims to recruit 1,700 diabetic patients (including 200 with type 1 diabetes mellitus (independent of healthcare setting)) attending the hospitals and primary care and to collect the following data:
- Demographics: age, sex, ethnicity, socio-economic background, smoking status;
- Anthropometrics: vital signs, height, weight, body fat percentage, fat mass, neck and waist circumference;
- Medical History: medications, complications, comorbidities, latest HbA1c and lipid profiles and family medical history;
- Routine laboratory data;
- Lifestyle: diet, physical activity,;
- Sleep: quality and daytime sleepiness;
- Cognition and Mental Health: depression, anxiety, stress and memory;
- Diabetes microvascular complications: diabetic neuropathy, urine albumin/creatinine ratio; routine retinal screening data.
- Gut microbiome from a stool sample
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Type 1 and Type 2 diabetes mellitus;
- •Male or Female;
- •Resident in Qatar;
- •MENA birthplace and family origin;
- •18-70 years old;
- •Capable to give informed consent and complete the study.
排除标准
- •Known pregnancy or planning pregnancy during the duration of study;
- •Congenital disorders;
- •Terminal illness;
- •Enrolled in a clinical trial involving medication;
- •Uncontrolled mental illness preventing participation;
- •Those who have already experienced a definitive microvascular complication:
- •i. End-stage renal disease; ii. Major amputation; iii. Blindness.
结局指标
主要结局
Diabetes Complications (Nephropathy, Neuropathy, Retinopathy)
时间窗: Baseline (Cross-Sectional)
Our primary analyses will be conducted to explore the potential cross-sectional relationships amongst proposed factors related to type 2 diabetes complications
次要结局
- Sleep and sleep related breathing disorders(Baseline (Cross-Sectional))
- Mental Health(Baseline (Cross-Sectional))
- Physical activity(Baseline (Cross-Sectional))