NL-OMON48464已完成4 期
Adjustment of insulin Degludec to Reduce post-Exercise (nocturnal) hypoglycaeMia in people with diabetes - the ADREM study - ADREM
Afdeling Interne Geneeskunde0 个研究点目标入组 18 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 18
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Adults with type 1 diabetes mellitus, 18-60 years
- •Diabetes duration at least two years
- •Treatment with long-acting insulin in combination with short-acting insulin
- •analogue, according to basal-bolus regimen for at least one year
- •Stable glycaemic control with HbA1c <=75 mmol/mol (9%)
- •At least one severe hypoglycaemia in the past year and/or >=2 points on Dutch
- •modified version of Clarke score or >=3 points on Gold score
- •Regularly engaging in exercise of moderate intensity or more (at least one
- •hour per week)
排除标准
- •Microvascular complications, except background retinopathy or microalbuminuria
- •History of cardiovascular disease, including heart failure, symptomatic
- •cardiac valve disease and treatment-requiring arrhythmia
- •Use of drugs affecting glucose metabolism other than insulin or metformin
- •BMI >30 kg/m2
- •Blood pressure >160/90 mmHg or use of blood pressure lowering drugs
- •Pregnancy or the wish to become pregnant
- •MDRD-GFR <60 ml/min/1.73 m2
研究者
相似试验
进行中（未招募）
1 期
Adjustment of the dose of long acting insulin (Degludec) to reduce low glucose after exercise in patients with type 1 diabetestype 1 diabetes mellitusEUCTR2019-004222-22-NLRadboud University Medical Center18
招募中
不适用
Adequate adjustment from insulin degludec to insulin pump therapy in patient with type 1 diabetestype 1 diabetesJPRN-UMIN000013136Department of Pediatrics Osaka City University Graduate School of Medicine20
尚未招募
不适用
Evaluating the effect of intraoperative dextrose 10% administration on reducing post-operative nausea and vomiting after laparoscopic surgery.PACTR201808847015879ashraf nabil130
招募中
不适用
Investigation of the usefulness of insulin degludec in patients with type 1 diabetestype 1 diabetesJPRN-UMIN000010893Division of Diabetes, Endocrinology and Metabolism, Department of Internal Medicine, Hyogo College of Medicine20
进行中（未招募）
不适用
The effect of insulin degludec in combination with liraglutide and metformin in subjects with type 2 diabetes qualifying for treatment intensificatioMedDRA version: 14.1Level: LLTClassification code 10045242Term: Type II diabetes mellitusSystem Organ Class: 10027433 - Metabolism and nutrition disordersDiabetes Mellitus, Type 2EUCTR2011-004665-32-GBovo Nordisk A/S320