NCT01861613已完成4 期
Seroprevalence of Hepatitis B and Immune Response to Hepatitis B Vaccination in Chinese College Students
Hui Zhuang1 个研究点 分布在 1 个国家目标入组 2,040 人开始时间: 2009年9月1日最近更新:
适应症
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 2,040
- 试验地点
- 1
- 主要终点
- Anti-HBs immune response in participants negative for HB sAg, anti-HBs and anti-HBc
研究概览
简要总结
At present, children less than 15 y of age have been regarded as a key group for hepatitis B immunization in China. However, there is not yet special immunization strategy for population above 15 y of age. In this study, we investigated the seroprevalence of hepatitis B and immune response to HB vaccine among Chinese college students to uncover the need on universal mass vaccination or booster immunization only for students with HBV vaccination history against hepatitis B in Chinese college students to inform decision making.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 16 Years 至 30 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Male and female freshmen in one college in Liuzhou city of Guangxi Zhuang Autonomous Region
排除标准
- •for vaccination study:
- •acute illness
- •immunocompromised conditions
- •renal insufficiency
- •pregnancy
- •allergic history to HB vaccine or yeast
- •positive for any of HBsAg, anti-HBs or anti-HBc
结局指标
主要结局
Anti-HBs immune response in participants negative for HB sAg, anti-HBs and anti-HBc
时间窗: Anti-HBs was assayed at Month 7
次要结局
- Seroprevalence for HBsAg, anti-HBs and anti-HBc in Chinese college students(seroprevalence at baseline)
- Anti-HBs immune response in participants negative for HBsAg, anti-HBs and anti-HBc(Anti-HBs immune response at Month 20)
研究者
Hui Zhuang
Professor
Peking University
研究点 (1)
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