NCT00188175已完成2 期
A Phase II Study of Preoperative Intensity-Modulated Radiation Therapy For Lower Limb Soft Tissue Sarcoma
适应症
干预措施
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 59
- 试验地点
- 2
- 主要终点
- Major wound complications within 120 days following surgery
研究概览
简要总结
Intensity-modulated radiation therapy may make wound healing problems less likely by 1)precisely shaping the region of high radiation dose to the shape of the tissue which harbours tumour cells, and 2) precisely shaping the regions of low radiation dose to the shapes of the normal tissues which are more sensitive to radiation effects.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 16 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Histologically proven soft tissue sarcoma
- •Lesion lies between the iliac crest (hipbone) and the ankle
- •Lesion is newly diagnosed
- •Assessed by radiation oncologist and surgical oncologist
排除标准
- •Benign histologies
- •Histologies generally treated with chemotherapy
- •Prior or recurrent cancer, except nonmelanomatous skin cancer or carcinoma in-situ of the cervix
研究组 & 干预措施
IMRT for lower limb soft tissue sarcoma
Experimental
干预措施: Intensity Modulated Radiation Therapy (Radiation)
结局指标
主要结局
Major wound complications within 120 days following surgery
时间窗: 120 days post-op
次要结局
- Assess acute and late radiation toxicity including limb edema(up to120 days)
研究者
研究点 (2)
Loading locations...
相似试验
招募中
2 期
A Study of Radiation Therapy After Surgery in People With Oral Tongue Squamous Cell CarcinomaOral Tongue Squamous Cell CarcinomaNCT06485778Memorial Sloan Kettering Cancer Center24
Unknown
2 期
Preoperative Concurrent Chemotherapy and Intensity Modulated Radiotherapy (IMRT) in Locally Advanced Rectal CancerRectal Cancers.NCT01340508National University Hospital, Singapore63
招募中
2 期
Preoperative Radiotherapy and Immunotherapy for Sinonasal and Anorectal Mucosal MelanomaNCT05546827M.D. Anderson Cancer Center40
Unknown
2 期
Postoperative IMRT Combined With Capecitabine for Advanced Gastric Cancer PatientsGastric CancerNCT01674959Chinese Academy of Medical Sciences40
已完成
2 期
Intensity-Modulated Radiation Therapy, Cisplatin, and Bevacizumab Followed by Carboplatin and Paclitaxel in Treating Patients Who Have Undergone Surgery for Endometrial CancerEndometrial AdenocarcinomaEndometrial Adenosquamous CarcinomaEndometrial Clear Cell AdenocarcinomaEndometrial Serous AdenocarcinomaStage IA Uterine Corpus Cancer AJCC v7Stage IB Uterine Corpus Cancer AJCC v7Stage II Uterine Corpus Cancer AJCC v7Stage IIIA Uterine Corpus Cancer AJCC v7Stage IIIB Uterine Corpus Cancer AJCC v7Stage IIIC Uterine Corpus Cancer AJCC v7Stage IVA Uterine Corpus Cancer AJCC v7Stage IVB Uterine Corpus Cancer AJCC v7NCT01005329National Cancer Institute (NCI)34