Ultrasound-guided Transversus Abdominis Plane Block for Postoperative Analgesia in Living Donor Hepatectomy: Randomized Controlled Double-blinded Trial
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 50
- 主要终点
- pain scores (at movement and at rest)
研究概览
简要总结
Living donor organ transplantation has increased in recent years due to an increased need for organs. The objective of this study was to investigate the effects of a TAP block on postoperative analgesia and opioid consumption in liver transplantation donors in whom a right lateral extending upper mid-line abdominal incision was used.
详细描述
This prospective randomized controlled double-blinded study was conducted with 50 liver transplantation donors between 18-65 years who were scheduled to undergo right hepatectomy surgery. Cases to whom TAP block with ultrasound was applied after standard general anesthesia were determined as Group 1 and cases to whom only standard general anesthesia was applied, were determined as Group 2.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Liver transplantation donors
排除标准
- •Patients with a history of allergy to the drugs used in the study protocol, coagulation pathology, opioid tolerance
研究组 & 干预措施
transversus abdominis plane block
Patients who received a tranversus abdominis plane block with ultrasound after standard general anesthesia represented Group 1.
The tranversus abdominis plane block was performed bilaterally by obtaining an image with real time ultrasound guidance with a 6-13 MHz linear probe.
The block was placed with a 22 G 80 mm needle while obtaining real-time images via an in-plane technique.
Two 20 mL syringes were prepared after preparing a local anesthetic concentration of 1.5 mg/kg of 0.5% bupivacaine to 40 mL with saline. These were administered to the left and right abdominal walls.
Postoperative analgesia was administered through a morphine the patient-controlled analgesia device.
干预措施: Transversus Abdominis Plane Block (Drug)
nonblocked
Patients who received standard general anesthesia alone made up Group 2. Postoperative analgesia was administered through a morphine the patient-controlled analgesia device.
干预措施: standard general anesthesia (Drug)
结局指标
主要结局
pain scores (at movement and at rest)
时间窗: postoperatively at 24 hours
Pain scores were assessed using a visual analog scale (0: No pain, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10: Excruciating pain).
次要结局
- morphine consumption(postoperatively at 24 hours)
研究者
Mehmet Ali Erdoğan
Associted professor
Inonu University