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临床试验/NCT07808541
NCT07808541已完成不适用

Juntas Adelante: A Peer-Coaching Intervention to Promote Chemoprophylaxis for HIV Prevention Among Latina Transgender Women in the Washington DC Metropolitan Area.

George Washington University1 个研究点 分布在 1 个国家目标入组 39 人开始时间: 2024年10月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
39
试验地点
1
主要终点
PrEP initiation/persistence and/or PEP use

研究概览

简要总结

The goal of this clinical trial is to evaluate the impact of the Juntas Adelante intervention on awareness and use of chemoprophylaxis for HIV prevention (Pre- and Post-Exposure prophylaxis, or PrEP and PEP) among Latina Transgender Women in the Washington DC Metropolitan Area. Secondary outcomes included awareness and use of Doxy-PEP (i.e., Doxycycline for prevention of Sexually Transmitted Infections - STI), and awareness of Undetectable = Untransmittable (U=U).

The main questions are:

  1. Is the Juntas Adelante intervention acceptable and feasible to implement with this population?
  2. Is participating in the Juntas Adelante intervention associated with increased awareness and use of PrEP and PEP? All participants in the study will view 5 online short videos on HIV and STI prevention and will receive up to two virtual coaching sessions with a peer coach. They will also complete a brief survey after viewing each video (5 total) and three longer surveys/interviews over the course of 3 months.

详细描述

Using a community-based participatory research (CBPR) approach, we developed Juntas Adelante, an intervention to increase awareness and use of PrEP and PEP for HIV prevention among Latina transgender women in the DC metropolitan area. The Juntas Adelante intervention includes two components:

  1. Peer coaching sessions: Up to two virtual coaching sessions with another Latina transgender woman (peer coach) who has been trained to encourage dialogue around HIV prevention goals.
  2. Video mini-series: Five short informational videos covering 5 topics (one per episode): 1) Latina transgender women and HIV (duration: 2:29 min); 2) Post-exposure prophylaxis - PEP (duration: 3:49 min); 3) Pre-exposure prophylaxis - PrEP (duration: 1:58 min); 4) Doxy-PEP (duration: 3:25 min); and 5) Undetectable equals Untransmittable - U=U (duration: 3:47 min). Videos were housed into the Vimeo platform, and were embedded into REDCap surveys for distribution.

Participant recruitment and eligibility: Participants will be recruited via referrals from community members (i.e., members of the Community Council, other study participants). Eligibility criteria include: 1) Male sex assigned at birth, currently identifying as a woman, transgender woman, transgender, or transsexual, irrespective of gender transition stage; 2) identifying as Latina, regardless of country of birth; 3) being 18 years old or older; 4) living in the DC metropolitan area; 5) self-reporting HIV negative status at study enrollment 6) reporting having receptive anal and/or neovaginal sex with at least one cisgender man or transgender woman in the previous 12 months; 7) not currently using PrEP or report less than 3 months of use; 8) have access to a cellphone with internet capabilities, and 9) not planning to move from the DC metropolitan area in the next 12 months.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Other
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
Male
接受健康志愿者

入选标准

  • Male sex assigned at birth, currently identifying as a woman, transgender woman, transgender, or transsexual, irrespective of gender transition stage;
  • Identifying as Latina, regardless of country of birth;
  • Being 18 years old or older;
  • Living in the DC metropolitan area;
  • Self-reporting HIV negative status at study enrollment
  • Reporting having receptive anal and/or neovaginal sex with at least one cisgender man or transgender woman in the previous 12 months;
  • Not currently using PrEP or report less than 3 months of use;
  • Must have access to a cellphone with internet capabilities,
  • Not planning to move from the DC metropolitan area in the next 12 months

排除标准

  • - Not meeting all of the inclusion criteria.

研究组 & 干预措施

Intervention

Experimental

干预措施: Juntas Adelante: A Peer coaching Intervention to Promote Chemoprophylaxis for HIV Prevention among Latina Transgender Women in the Washington DC Metropolitan Area. (Behavioral)

结局指标

主要结局

PrEP initiation/persistence and/or PEP use

时间窗: "Final follow up, 3 months after last coaching session"

Our primary outcome is PrEP initiation/persistence or PEP use at the 3-month follow up, defined as the combination of any: 1. PrEP Initiation: Participants who reported having never used PrEP at baseline AND report starting PrEP between baseline and 3-month follow up OR participants who reported having ever used PrEP but were not currently using at baseline AND report re-starting PrEP between baseline and 3-month follow up. 2. PrEP Persistence: Participants who reported using PrEP at baseline AND continued using at 3-month follow up. For daily oral PrEP, persistence is defined as still taking PrEP at 3 month follow-up. Persistence for long-acting injectable PrEP will be defined as receiving at least 1 injection since baseline visit. 3. PEP Use: Any instance of PEP use by a non-PrEP user between baseline and 3-month follow up.

次要结局

  • Change in PrEP awareness(Baseline survey to final follow-up 3 months after last coaching session.)
  • Change in PEP awareness(Baseline survey to final follow-up 3 months after last coaching session.)
  • Change in Doxy-PEP awareness and use(Baseline survey to final follow-up 3 months after last coaching session.)
  • Change in U=U awareness(Baseline survey to final follow-up 3 months after last coaching session.)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Ana María del Río-González

Associate Professor

George Washington University

研究点 (1)

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