NCT01220414已完成不适用
Attenuation of Pain in Men and Women: Mechanisms of Exercise-Induced Analgesia
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Time for Subject to Reach Pain Threshold
研究概览
简要总结
The purpose of this study is to examine opioid and endocannabinoid mechanisms of exercise-induced analgesia in men and women.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy men and women
排除标准
- •current cardiac or other chronic diseases (e.g., cancer, diabetes, hypertension, kidney disease); routine use of prescriptive medications; history of vasovagal response to phlebotomy; an allergy to naltrexone; pregnancy; current smokers; current use of recreational drugs; history of substance abuse
研究组 & 干预措施
Men
Active Comparator
干预措施: Placebo, then Naltrexone (Drug)
Men
Active Comparator
干预措施: Naltrexone, then placebo (Drug)
Women
Active Comparator
干预措施: Naltrexone, then placebo (Drug)
Women
Active Comparator
干预措施: Placebo, then Naltrexone (Drug)
结局指标
主要结局
Time for Subject to Reach Pain Threshold
时间窗: Baseline
次要结局
未报告次要终点
研究者
研究点 (1)
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