Does an International Version of ICISS Predict Mortality for Patients Admitted With Trauma in Four Public University Hospitals in Urban India?
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 16,047
- 主要终点
- Mortality
研究概览
简要总结
The aim of this study is to validate international versions of the International Classification of Disease Injury Severity Score (ICISS) in adult trauma patients admitted to four public university hospitals in urban India.
详细描述
Introduction
Trauma causes 10% of the world's annual deaths. Trauma-related deaths are most common in low- and middle-income countries, which accounts for over 90% of global trauma mortality. In 2013 over 1.2 million trauma deaths occurred in India alone. Hence, India accounted for 25% of trauma-related deaths worldwide. Experiences from high income countries show that the establishment of trauma registers have been of importance for the improvement of trauma care and research, allowing for comparisons between different hospitals as well as over time.
To be useful such comparisons should be risk-adjusted to account for differences in care and patient case mix. In trauma one of the most important patient case mix characteristics to adjust for is injury severity. Several different injury severity scores exist for this purpose. One of these scores is the International Classification of Disease Injury Severity Score (ICISS). In contrast to other established scores, such as the Injury Severity Score (ISS), ICISS can be calculated based on injuries coded using ICD for administrative purposes, making it cost effective.
The validity of ICISS has primarily been studied in high-income countries ICISS requires an empirically estimated Survival Risk Ratio (SRR) for each ICD code. Some studies from high income countries has shown similar predictive performance of ICISS when using SRRs derived from other high-income countries. However, the generalisability of such SRRs to low- and middle-income countries such as India has not been researched. Therefore, the aim of this study was to validate an international version of ICISS in patients presenting with trauma to four public university hospitals in urban India.
Study design
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •History of trauma or death between arrival and admission
排除标准
- •Isolated limb fractures without vascular injury
结局指标
主要结局
Mortality
时间窗: Within 30 days of patient arrival to participating centre
次要结局
- Mortality(Within 24 hours of patient arrival to participating centre)
研究者
Martin Gerdin
Researcher
Karolinska Institutet
