Sleep and Memory Consolidation in Adults With Attention Deficit Hyperactivity.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 36
- 主要终点
- Difference in signal power (db or μV 2) in the sigma frequency bands in N2 sleep
研究概览
简要总结
Attention Deficit Disorder With Hyperactivity is associated with deficits in cognition and sleep. In healthy adults, memory consolidation processes are related to sleep spindle activity in the sleep electroencephalogram. This association is poorly characterized in adults with attention deficit hyperactivity. In this study, the purpose is to characterize sleep microarchitecture disorders through the analysis of different stage of sleep EEG activity during a polysomnographic examination in adult with mixed Attention Deficit Disorder With Hyperactivity presentation compared to healthy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •for all participants:
- •Age from 18 to 45 years old
- •Affiliated to the French health care system
- •Inclusion Criteria for attention deficit hyperactivity disorder patients:
- •meeting Diagnostic and Statistical Manual (DSM)-5 criteria for mixed attention deficit hyperactivity disorder presentation without drug treatment for attention deficit hyperactivity disorder.
排除标准
- •for all participant:
- •People not able to give consent, neurological disease (other than neurodevelopmental disorders; or any other serious disease (cancer, addiction, systemic disease)), untreated sleep apnea, major depression (Beck inventory > 15), untreated restless leg syndrome; pregnancy in progress or wish to become pregnant during the study or breastfeeding woman, drug treatment including benzodiazepine, neuroleptic or antidepressant before inclusion.
- •Exclusion Criteria for healthy volunteers:
- •Subjective cognitive and/or sleep complaint.
研究组 & 干预措施
Attention Deficit Disorder With Hyperactivity
Patients with Attention Deficit Disorder With Hyperactivity. Same examinations than control group
干预措施: Neurological examinations (Other)
Control
Healthy volunteers Same examinations than Attention Deficit Disorder With Hyperactivity group
干预措施: Neurological examinations (Other)
结局指标
主要结局
Difference in signal power (db or μV 2) in the sigma frequency bands in N2 sleep
时间窗: 1 day
difference between 2 groups
次要结局
未报告次要终点