A clinical study to evaluate the efficacy of Yashtimadhu Taila Nasya in the management of Akal Palitya W.S.R. to Premature Graying of Hair
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- 1.Kesha varna(color of hair)Natural color of hair0
研究概览
简要总结
The face of an individual is a personal identity in which hair play a significant role. Healthy hair is a healthy sign of personality and youth. Everyone wants to look younger than their age and first thing they do is to hide their gray hair either by dyeing or some other ways. There is always a solution to every problem, same applies to canities (gray hair). So there is need to find a solution to make these canities to revert back to normal hair or stop the process of premature graying of hair. Akal Palitya or premature graying of hair is a disease pertaining to head and Nasya has been mentioned effective in Shiroroga. The information about the concept of Nasyakarma in Panchakarma and its importance is mentioned very well in Ayurvedic Samhita Granthas. In ayurveda nose is considered as the gateway of the head. The process of giving medication through nose is called Nasyakarma. It is considered as the best route of medication for the ailments pertaining to head. Acharya Sushrut, while mentioning the guna and importance of Nasya, has mentioned that Nasya is effective in Palitya rog in Sh.Ch. 40/22 . Acharya Cakardatta has mentioned Yashtimadhu Tailain 59th chapter, Netrarog Chikitsa. It has been told thattaking nasya of this taila for one month will make visionclear and make wrinkles and gray hairdisappear. Therefore Nasya is selected as route of administration for medication in Akal Palitya for clinical study. So this study will answer these questions of reversibility, stagnation of canities along with effectiveness of Nasya in Akal Palitya shall also be tested.
研究设计
- 研究类型
- Interventional
- 分配方式
- Random Number Table
- 盲法
- Open Label
入排标准
- 年龄范围
- 15.00 Year(s) 至 35.00 Year(s)（—）
- 性别
- All
入选标准
- •Patient aged between 15-35 years with premature graying of hair.
- •Patient fit for Nasya
- •Patient of either sex
- •Patient willing to participate in the study.
排除标准
- •Patients with any systemic disorder
- •Patients with any skin disease like albinism, leucoderma or vitiligo
- •Patients with hereditary disorder (Werner’s syndrome: diagnosis will be done on clinical grounds through thorough history of patient)
- •Patients with hormonal imbalance like hyperthyroid or hypothyroid
- •Patient with Megaloblastic Anemia
- •Any autoimmune disease.
结局指标
主要结局
1.Kesha varna(color of hair)Natural color of hair0
时间窗: Day 0: At the time of enrollment of patient for study | Day 30: At the end of treatment | Day 45: At first Follow up | Day 60: At second Follow up
White hair3
时间窗: Day 0: At the time of enrollment of patient for study | Day 30: At the end of treatment | Day 45: At first Follow up | Day 60: At second Follow up
2.Ruksha sphuttita kesha(dry split ends)
时间窗: Day 0: At the time of enrollment of patient for study | Day 30: At the end of treatment | Day 45: At first Follow up | Day 60: At second Follow up
Normal0
时间窗: Day 0: At the time of enrollment of patient for study | Day 30: At the end of treatment | Day 45: At first Follow up | Day 60: At second Follow up
Yellowish2
时间窗: Day 0: At the time of enrollment of patient for study | Day 30: At the end of treatment | Day 45: At first Follow up | Day 60: At second Follow up
Outcome will be assessed on following criteria and their respective scoring
时间窗: Day 0: At the time of enrollment of patient for study | Day 30: At the end of treatment | Day 45: At first Follow up | Day 60: At second Follow up
Dryness felt by touch2
时间窗: Day 0: At the time of enrollment of patient for study | Day 30: At the end of treatment | Day 45: At first Follow up | Day 60: At second Follow up
Split ends3
时间窗: Day 0: At the time of enrollment of patient for study | Day 30: At the end of treatment | Day 45: At first Follow up | Day 60: At second Follow up
Ash colored1
时间窗: Day 0: At the time of enrollment of patient for study | Day 30: At the end of treatment | Day 45: At first Follow up | Day 60: At second Follow up
Visible dryness1
时间窗: Day 0: At the time of enrollment of patient for study | Day 30: At the end of treatment | Day 45: At first Follow up | Day 60: At second Follow up
(burning sensation)
时间窗: Day 0: At the time of enrollment of patient for study | Day 30: At the end of treatment | Day 45: At first Follow up | Day 60: At second Follow up
3.Sanighad sthula (unctuous thick hair)
时间窗: Day 0: At the time of enrollment of patient for study | Day 30: At the end of treatment | Day 45: At first Follow up | Day 60: At second Follow up
Unctuous visible1
时间窗: Day 0: At the time of enrollment of patient for study | Day 30: At the end of treatment | Day 45: At first Follow up | Day 60: At second Follow up
Unctuous felt with
时间窗: Day 0: At the time of enrollment of patient for study | Day 30: At the end of treatment | Day 45: At first Follow up | Day 60: At second Follow up
Unctuous felt by touch2
时间窗: Day 0: At the time of enrollment of patient for study | Day 30: At the end of treatment | Day 45: At first Follow up | Day 60: At second Follow up
No burning sensation0
时间窗: Day 0: At the time of enrollment of patient for study | Day 30: At the end of treatment | Day 45: At first Follow up | Day 60: At second Follow up
split hair3
时间窗: Day 0: At the time of enrollment of patient for study | Day 30: At the end of treatment | Day 45: At first Follow up | Day 60: At second Follow up
4.Daha over scalp
时间窗: Day 0: At the time of enrollment of patient for study | Day 30: At the end of treatment | Day 45: At first Follow up | Day 60: At second Follow up
Mild burning sensation 1 (localized)
时间窗: Day 0: At the time of enrollment of patient for study | Day 30: At the end of treatment | Day 45: At first Follow up | Day 60: At second Follow up
Severe burning sensation 3 (all over the scalp)
时间窗: Day 0: At the time of enrollment of patient for study | Day 30: At the end of treatment | Day 45: At first Follow up | Day 60: At second Follow up
Moderate burning sensation 2
时间窗: Day 0: At the time of enrollment of patient for study | Day 30: At the end of treatment | Day 45: At first Follow up | Day 60: At second Follow up
次要结局
- Random hair count will be done for counting number of gray hair. Scalp will be divided into five regions i.e. Frontal, Vertex, Right and Left Temporal and Occipital. One square centimeter area of scalp will be chosen where more gray hair are present, from this site gray hair would be counted randomly before and after the treatment.(Scoring of gray hair will be as follows:)