ISRCTN15653306已完成未知

Association of the neuroendocrine parameters of cortisol and adrenocorticotropin hormone (ACTH) during repeated exposure therapy with long-lasting therapy outcome in patients with panic disorder and agoraphobia: an observational study

Charité - University Medicine Berlin (Charité - Universitätsmedizin Berlin) (Germany)0 个研究点目标入组 20 人开始时间: 2009年12月8日最近更新: 2019年9月9日

试验速览

•1. Subject familiarised with experimental procedure and had given written informed consent
•2. Diagnosis of panic disorder with agoraphobia according to Diagnostic and Statistical Manual of Mental Disorders, 4th Edition (DSM IV), at least moderately ill
•3. Aged 18 - 75 years, either sex
•4. Sufficiently able to communicate with investigator, answer questions and fill in questionnaires
•5. Reachability of patient for treatment and follow-up
•6. Complience of patient
•7. Undisturbed day-night rhythm

•1. Inability to give informed consent
•2. Hospitalisation in a mental institution
•3. Other psychiatric illnesses like schizophrenia, substance abuse or dementia
•4. Acute suicidal tendency
•5. Epilepsy or other illness of the central nervous system (CNS) (e.g. brain tumour, encephalitis)
•6. Severe internal medical illness, e.g., severe hypertension, severe cardiac insufficiency, condition after acute myocardial infarction, cardiac arrhythmia of severity index IV or V according to Lown grade, severe dysfunction of liver or kidney, diabetes mellitus requiring insulin treatment, disturbances of haematopoiesis
•7. Pregnancy or breastfeeding
•8. Changes of psychopharmacological treatment within the last 8 weeks or discontinuation of psychopharmacological treatment within less than 2 weeks before beginning of the study
•9. Recent interference with diurnal cycle
•10. Current psychotherapeutic treatment specific for panic disorder and/or agoraphobia
•11. Participation in other study within last month before beginning of the study or during the study

发起方

Charité - University Medicine Berlin (Charité - Universitätsmedizin Berlin) (Germany)