The Predictive Role of Glucose/Potassium Ratio for Mortality in Patients With Major Burn Trauma
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Glucose-to-potassium ratio
研究概览
简要总结
The aim of this observational study is to investigate the role of the glucose-potassium ratio in predicting mortality in patients with major burn trauma.
The main question it aims to answer is: Can the glucose-potassium ratio predict mortality in major burn patients? The glucose-to-potassium ratios of major burn patients at the time of initial hospitalization will be determined, and their relationship with mortality will be analyzed.
详细描述
Major burns, especially electrical burns, facial burns, inhalation burns, burns with large burn surface areas, and deep burns, have a high mortality risk. Early detection of this risk may be critical to reducing mortality rates. For this reason, trauma centers are working on rapid and effective prognostic markers. In trauma and stress situations, glucose levels rise while potassium levels fall due to increased catecholamines. The literature reports that hyperglycemia, also known as the glucose-potassium ratio, can rapidly and effectively predict morbidity and mortality in patients suffering from subarachnoid hemorrhage, pulmonary embolism, traumatic brain injury, or blunt abdominal trauma. Many publications show that increased glucose is associated with mortality and morbidity in critical illnesses and trauma. The isolated glucose-potassium ratio has a higher predictive ability for mortality and morbidity compared to glucose and potassium levels. In this study, investigators aimed to examine the prognostic value of the glucose-to-potassium ratio in participants with major burn trauma.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All burns >40% of total body surface area (2nd degree or deeper)
- •Burns with inhalation injury
- •Burns >20% of total body surface area 3nd degree or deeper
排除标准
- •First degree burns
- •Patients have more than 24 hours since the onset of burn trauma
- •Patients with diabetes mellitus
- •Patients with chronic renal failure
- •Patients taking potassium-modifying medication
- •Patients with missing data
结局指标
主要结局
Glucose-to-potassium ratio
时间窗: 2 days
The glucose-to-potassium ratio is calculated by dividing the participants' glucose values when they first apply to the hospital by their potassium values.
次要结局
- Burn infection rate(2 days)
- Mean percent of total body surface area burned(2 days)
- Mortality rate(2 days)
- Female/Male ratio(2 days)
研究者
Alpaslan Şahin
Principal investigator
Konya Meram State Hospital
