KCT0006222尚未招募未知
Intensity-adjusted SAlvage chemotheraPy Plus FLT3-inHibitor Gilteritinib In RElapsed/refractory acute myeloid leukemia with mutated FLT3-ITD/TKD
适应症
试验速览
- 阶段
- 未知
- 状态
- 尚未招募
- 入组人数
- 26
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional Study
入排标准
- 年龄范围
- 19?(Year) 至 o Limit（—）
- 性别
- All
入选标准
- •Relapsed or refractory mutated FLT3-ITD/TKD AML
- •No prior exposure to Gilteritinib (prior exposure of other FLT3-inhibitors is permitted including quizartinib or midostaurin)
- •Mean QTcF interval of ECG readings is 480 ms or shorter
- •Written informed consent must be given.
- •Patients must be 19 years of age or older.
排除标准
- •prior exposure to gilteritinib
- •Patients who are not able to receive FLAG-Ida or LoDAC
- •Acute promyelocytic leukemia with t(15;17) or PML/RARa rearrangement
- •Patients with CNS involvement of leukemic blasts will not be excluded.
- •Patients with extramedullary relapse(s) only will be excluded.
- •Uncontrolled active infection
- •Uncontrolled bleeding
- •Patients who are pregnant or lactating.
- •Patients having a psychiatric disorder or mental deficiency severe as to make compliance with the treatment unlike, and making informed consent impossible.
研究者
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