Outcome of Women With Cervical Cancer
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 81
- 试验地点
- 1
- 主要终点
- Outcome of women with cervical cancer
研究概览
简要总结
Squamous cell carcinoma (SCC) of the cervix has showed a marked decline in developed countries over the past 40 years, however, there has also been an increase in relative and absolute incidence of adenocarcinoma and adenosquamous carcinoma (AC) of the uterine cervix over the same period.
Our understanding of the natural history and optimal management of AC is limited. It appears that AC and SCC of the cervix behave differently. They are different in epidemiology, prognostic factors, and patterns of failure after similar treatments. Available data suggest that they may also differ in their response to treatment. We postulate that new treatment strategies specifically tailored to AC should be explored.
However, there is few data about outcome of cervical cancer in Taiwan. So we propose this proposal for retrospective analysis of clinicopathological parameters and outcomes in patients of cervical cancer, especially for cervical adenocarcinoma and adenosquamous carcinoma.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 20 Years 至 99 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Time interval: from 1991 to date.
- •Comprehensive surgical staging, debulking procedure, radiotherapy or chemotherapy.
- •All female patients with cervical cancer who underwent treatment for cervical cancer at Far Eastern Memorial Hospital.
- •All the patients diagnosed as cervical cancer, especially for women with adeno- and adenosquamous carcinoma.
- •To review:
- •Clinical data: including age at diagnosis, presenting symptoms, gravidity, parity, menstrual history, body mass index, history of diabetes, hypertension, personal history of cancer and staging.
- •Pathologic information: deep stromal invasion, lymph-vascular space invasion, lymph node involvement, parametrium invasion, vaginal cut end and tumor size.
- •Survival data: disease-free and overall survival.
- •Radiation report, Chemotherapy treatment, operation, discharge and admission note.
排除标准
- •Not comprehensive staging/debulking procedure.
- •Patients who died of postoperative complications within 30 days after surgery were excluded from the survival analysis.
- •Female minors or disabled persons.
结局指标
主要结局
Outcome of women with cervical cancer
时间窗: 20 years
次要结局
未报告次要终点
研究者
Sheng-Mou Hsiao
Chief, Department of Obstetrics & Gynecology
Far Eastern Memorial Hospital