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临床试验/NCT00194350
NCT00194350已完成不适用

Evaluation of the Role of Factor V Leiden Mutation in Implantation Failure

University of Pennsylvania1 个研究点 分布在 1 个国家目标入组 399 人开始时间: 2001年9月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
399
试验地点
1

研究概览

简要总结

The purpose of this study is to determine whether inherited thrombophilias (tendency toward blood clotting) increase the risk of failure of the embryo to implant in IVF. The specific condition to be studied is the presence or absence of the Leiden mutation of the Factor V gene.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
Female
接受健康志愿者

入选标准

  • Women undergoing in-vitro fertilization with successful ovarian hyperstimulation, oocyte retrieval, and fertilization
  • Transfer of at least 2 fresh embryos of Grade 2 (preembryo with blastomeres of equal size and <=10% cytoplasmic fragmentation) or better

排除标准

  • Infertility due to uterine anatomic defect
  • Current use of anticoagulant medication, such as heparin or aspirin
  • Known presence of any other condition associated with increased risk of thrombosis

研究者

申办方类型
Other

研究点 (1)

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Factor V Leiden Mutation and Implantation Failure | 临床试验