NCT07635082已完成2 期
Extended Letrozole Protocol Versus Letrozole Plus Inositol for Induction of Ovulation in Letrozole Resistant PCOS Women
Eman Basuni Ebrahim Mowad1 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2024年2月1日最近更新:
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 200
- 试验地点
- 1
研究概览
简要总结
Extended letrozole protocol versus letrozole plus Inositol for Induction of ovulation in letrozole resistant PCOS Women
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Women diagnosed with polycystic ovary syndrome (PCOS) according to the Rotterdam criteria.
- •Letrozole-resistant PCOS patients who failed to ovulate after receiving letrozole 5 mg daily for 5 days for three consecutive cycles.
- •Age 18 to 35 years.
- •Body mass index (BMI) ≤ 30 kg/m².
- •Normal uterine cavity and patent fallopian tubes confirmed by hysterosalpingography (HSG) and/or laparoscopy.
- •Partner with normal semen analysis.
- •Willing and able to provide informed consent.
排除标准
- •Thyroid dysfunction.
- •Hyperprolactinemia.
- •Diabetes mellitus.
- •Congenital adrenal hyperplasia.
- •Adrenal causes of hyperandrogenism.
- •Use of insulin-sensitizing medications (e.g., metformin) during the study period.
- •Chronic liver disease.
- •Chronic kidney disease.
- •Contraindications to pregnancy.
- •Contraindications or hypersensitivity to inositol or letrozole.
研究者
Eman Basuni Ebrahim Mowad
Teaching assistant
Kafrelsheikh University
研究点 (1)
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