The Incidence, Risk Factors and Outcomes of Electrolytes Disturbances in Critically Ill Egyptian Patients: A Single-Centre Prospective Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 入组人数
- 110
- 试验地点
- 1
- 主要终点
- impact of electrolytes imbalances for general health status
研究概览
简要总结
All selected individuals will be subjected to the following:
- Full medical history taking
- Full clinical examination, APACHE II score on admission
- Electrolytes panel daily on ICU admission
- Estimate the duration of stay at ICU Also all selected individuals will be sectioned into groups regarding sites of collection (surgical ICU, CCU and medical ICU). All collected individuals will be sectioned regarding electrolytes imbalance into mild, moderate and severe groups
详细描述
Study Procedures: All selected individuals will be suffering from electrolyte imbalance (EI) with the following data will be obtained:
o Measurements:
- Demographic data: age - gender - BMI - electrolytes data on ICU admission
- Vital data: heart rate - respiratory rate - blood pressure measurement - Oxygen saturation - Urinary output - Temp +/- CVP measurement.
- Lab.: "CBC - Kidney function tests - liver function tests - ABG - levels of serum sodium, potassium, magnesium, phosphorus, ionized calcium and chloride", with maximum 5 mm blood sampling per day. Serum-sodium levels will be corrected for serum-glucose by lowering the sodium concentration by 2.4 mmol/L for every 100 mg/dl increase in glucose. Corrected Sodium = Measured sodium + 0.016 (Serum glucose - 100) A correction formula was also used to calculate albumin-corrected calcium levels (mmol/L) Corrected Calcium = (0.8 (Normal Albumin - Pt's Albumin)) + Serum Ca
- APACHE II score
- Comorbidities
- Complications: AKI- Acute myocardial infarction
- Duration of ICU stay
- Duration of hospital stay
- Outcome (regarding eventual complications: AKI- Acute myocardial infarction)
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients admitted to medical ICU, surgical ICU and CCU suffering from electrolyte imbalance (EI) over 18 years with the comorbid conditions :
- •Hypertension
- •Heart failure
- •Chronic chest diseases
- •Chronic kidney disease
- •Diabetes mellitus
- •Cardiac dysrhythmias
- •Dehydration
- •Critical bones fractures
排除标准
- •Patients with
- •Age less than 18 year old
- •Patient or his 1st degree relatives refuse to participate
- •Patients without electrolytes data
- •Current smoking
结局指标
主要结局
impact of electrolytes imbalances for general health status
时间窗: 1 year
Laboratory: levels of serum sodium "mmol/L", potassium "mmol/L", magnesium "mg/dl", phosphorus "mg/dl", ionized calcium "mmol/L" and chloride "mmol/L", with maximum 5 mm blood sampling per day. Serum-sodium levels will be corrected for serum-glucose by lowering the sodium concentration by 2.4 mmol/L for every 100 mg/dl increase in glucose. Corrected Sodium = Measured sodium + 0.016 (Serum glucose - 100). A correction formula was also used to calculate albumin-corrected calcium levels (mmol/L). Corrected Calcium = (0.8 (Normal Albumin - Pt's Albumin)) + Serum Ca
次要结局
- impact of electrolytes imbalances for hospital stay(1 year)