The relationship between visual hallucinations, visual perception and attention in patients with schizophrenia - INZICHT

niversitair Medisch Centrum Groningen0 个研究点目标入组 51 人开始时间: 待定最近更新: 2024年6月11日

适应症

试验速览

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•For patients:
•1) meeting DSM-IV criteria for schizophrenia, schizophreniform disorder, schizoaffective disorder or psychotic disorder NOS;
•2) in case of psychiatric comorbidity, the schizophrenia spectrum disorder is predominating;
•3) age between 18-55;
•4) speaking Dutch fluently;
•5) being able to give informed consent.;Healthy controls must fulfill the following criteria:
•1) age between 18-55;
•2) speaking Dutch fluently;
•3) being able to give informed consent.

•1) other psychiatric disorders than above mentioned schizophrenia spectrum disorders; that presumably affect our data;
•2) the presence of accompanying neurological disorders that supposedly influence our data;
•3) visually acuity less than 50 percent (Snellen chart);
•4) visually field defects (Donders technique);
•5) cognitive impairment, which is assessed by Mini-Mental State Examination. The cut-off point is <26.
•Exclusion criteria fMRI:
•6) presence of implantable devices (electronically, magnetically or mechanically activated, for example implanted insuline pumps, cardiac pacemakers, cardioverter-defibrillators, metallic prosthetic heart valves, cochlear implants);
•7) medical disorders because of which patient are unable to lie flat for about 30 minutes, for example poorly controlled heart failure and poorly controlled or severe respiratory disease;
•8) ferromagnetic clips;
•9) intraocular metallic bodies;
•10) pregnancy;
•11) claustrophobia;
•12) colored tattoos;
•13) coils (exception: Mirena);
•14) weighing more than 140 kg.;Furthermore, healthy controls are being excluded if they ever have had a psychotic episode; or experience VH (besides due to severe sleep deprivation or use of medication/alcohol/drugs), or if they have a first degree family member who had a psychotic episode or has a psychotic disorder.

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