NL-OMON42685已完成不适用
Sensory axons in multifocal motor neuropathy (MMN) - Sensory axons in MM
niversitair Medisch Centrum Utrecht0 个研究点目标入组 20 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 20
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •1. Diagnosis of MMN according to internationally accepted criteria of the European Federation of Neurological Societies and Peripheral Nerve Society (EFNS/PNS criteria).
- •2. One median nerve (left or right) with any of the follwing abnormalities in the motor nerve conduction studies:
- •a) conduction block in motor axons in the forearm segment, defined as segmental reduction of compound muscle action potential (CMAP) area of at least 30%;
- •b) signs of demyelination: conduction velocity decrease up to 38 m/s or less and/or DML 5.3 ms or more and/or increase CMAP duration in the forearm of at least 30%;
- •c) motor axon loss defined as decreased CMAP amplitude of 3 mV or less;
- •3. Age range 18-99 years old.
排除标准
- •1. Other causes for neuropathy than MMN, including carpal tunnel syndrome (CTS).
- •2. Use of medication affecting ion-channels in nerves.
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