Correlation study for expression of peripheral blood Th17/Treg cell axis in HSPN patients

Hubei University of Traditional Chinese Medicine0 个研究点开始时间: 待定最近更新: 2023年2月20日

试验速览

暂无简介。

•1.Inclusion criteria of study group(HSPN subjects) :
•1) Aged 18-60 years;
•2) In accordance with diagnostic criteria of HSPN in the Clinical Guidelines-Nephrology Section which was edited by the Chinese medical association in 2011;
•3) eGFR >=60 (mL/min / 1.73 m2; the MDRD formula);
•4) 24-h UTP <=3.0 g;
•5) Willing to provide informed consent and complete the process required by the study.
•2.Inclusion criteria of control group (healthy subjects):
•1) Aged 18-60 years;
•2) Routine items such as blood, urine, feces, liver and kidney functions, and blood lipids are within the normal range in medical examination reports;
•3) To provide informed consent.

•1.Exclusion criteria of study group(HSPN subjects) :
•1) Women during pregnancy or lactation;
•2) Participating in interventional clinical trials
•3) Patients who have been treated with glucocorticoids and immunosuppressants for the past 3 months or are being treated due to HSPN;
•4) I or II type diabetes;
•5) NYHA Class III or IV heart failure;
•6) Viral hepatitis or cirrhosis;
•7) HIV infection or AIDS;
•8) Malignant tumors;
•9) Have been receiving dialysis for more than 1month, and/or organ or bone marrow transplantation;
•10) Have been diagnosed as polycystic kidney and other hereditary kidney diseases.
•2.Exclusion criteria of control group(healthy subjects) :
•1) Persons who have a history of chronic diseases such as hypertension, diabetes, coronary heart disease, hyperuricemia or hyperlipidemia;
•2) Persons who have a history of genetic diseases;
•3) Patients with immunological and allergic diseases;
•4) Patients with malignant tumors.

发起方

Hubei University of Traditional Chinese Medicine