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临床试验/NCT05602753
NCT05602753招募中不适用

Carbon Monoxide Breath Testing Prior to Total Joint Arthroplasty to Ascertain Smoking and Aid in Encouraging Smoking Cessation

McGill University Health Centre/Research Institute of the McGill University Health Centre1 个研究点 分布在 1 个国家目标入组 300 人开始时间: 2021年2月18日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
300
试验地点
1
主要终点
True incidence of smokers among patients undergoing joint replacement

研究概览

简要总结

The primary outcome of this study is to determine the true incidence of smokers among patients undergoing joint replacement and secondly, what percent are able to quit smoking before surgery under a structured cessation program with carbon monoxide breath testing. The investigators hypothesize that self-reported smoking status is underreported and that routine carbon monoxide breath testing will improve abstinence rates at the time of surgery.

详细描述

This study looks at patients who have been referred to our clinic for a potential hip and knee joint replacement surgery. Once it has been determined that the patient requires surgical replacement of either their hip or knee and is placed on our surgical waitlist, the patient will be asked if he or she would like to participate in the study. The investigators would ask all patients, both self-declared smokers and non-smokers, to participate. This study would include completing a smoking history questionnaire and a noninvasive carbon monoxide breath test. While smoking status is already assessed in the McGill University Health Centre preoperative questionnaire, the investigators intend on expanding these questions in study participants to better quantify their nicotine exposure.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 85 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Adults ages 18-85 who require a primary total hip or knee replacement
  • Any gender
  • Smokers and non-smokers
  • Osteoarthritis, rheumatoid arthritis, avascular necrosis

排除标准

  • Patients who require revision surgery
  • Previous fracture to affected area
  • Emergency surgery
  • Patients who do not understand, read or communicate in either French or English

结局指标

主要结局

True incidence of smokers among patients undergoing joint replacement

时间窗: 15 minutes

The percentage of subjects who declare themselves as smokers and non-smokers with elevated Co2 levels.

次要结局

  • To determine the incidence of patients who successfully quit smoking prior to surgery.(20 minutes)

研究者

发起方
McGill University Health Centre/Research Institute of the McGill University Health Centre
申办方类型
Other
责任方
Principal Investigator
主要研究者

Adam Hart

Principal Investigator, Staff Orthopaedic Surgeon

McGill University Health Centre/Research Institute of the McGill University Health Centre

研究点 (1)

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