Energy Value of Lentils and Chickpeas
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 18
- 试验地点
- 2
- 主要终点
- Energy excreted in feces and urine
研究概览
简要总结
This study is being conducted to determine the digestibility of and available energy from pulses.
详细描述
Previous studies have demonstrated that the metabolizable energy (energy available to the body) from tree nuts is less than predicted by the Atwater factors (the standard approach to determining calorie value of a food). The Atwater approach is over 100 years old and is inaccurate for some foods. This study will be conducted to determine the metabolizable energy from two pulses, lentils and chickpeas. The study will be a human nutrition intervention involving consumption of a controlled diet followed by collection of urine and feces.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Double (Investigator, Outcomes Assessor)
盲法说明
Treatments will be color coded, and samples will be labeled only by subject number and date. Investigators and outcomes assessors will not know the treatments nor the color code until after the data analyses are complete.
入排标准
- 年龄范围
- 25 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •BMI between 19 and 38 kg/m2
- •Age 25 to 75 years during intervention
排除标准
- •Known (self-reported) allergy or adverse reaction to study foods
- •Women who have given birth during the previous 12 months or who are pregnant/lactating or who plan to become pregnant during the study
- •History of bariatric surgery or nutrient malabsorption disease (such as celiac disease), Crohn's disease, diabetes, or metabolic disorders that may interfere with the study
- •History of certain cancer diagnosis or treatment in the last 3 years
- •Smoking or use of tobacco products in the past 6 months
- •Suspected or known strictures, fistulas or physiological/mechanical GI obstruction
- •Use of certain medications or supplements (prescription or over-the-counter) that may interfere with the study objectives, including blood thinning medications
- •Unable or unwilling to give informed consent or communicate with study staff
- •Self-report of alcohol or substance abuse within the past 12 months and/or current treatment for these problems (long-term participation in Alcoholics Anonymous is not an exclusion)
- •Other medical, psychiatric, or behavioral factors that in the judgment of the Principal Investigator may interfere with study participation or the ability to follow the intervention protocol
结局指标
主要结局
Energy excreted in feces and urine
时间窗: Cumulative from day 57-64
Energy (units of calories) excreted in feces and urine will be determined by bomb calorimetry.
次要结局
- Nitrogen excreted in feces and urine(Cumulative from day 10-17, day 39-46, day 57-64)
- Fat excreted in feces(Cumulative from day 10-17, day 39-46, day 57-64)
研究者
Janet Novotny
Research Physiologist
USDA Beltsville Human Nutrition Research Center