跳至主要内容
临床试验/NCT01132742
NCT01132742已完成不适用

Malnutrition and Outcome in Hospitalized Children in Europe (ESPEN Network Grant Project)

Ludwig-Maximilians - University of Munich14 个研究点 分布在 11 个国家目标入组 2,567 人开始时间: 2010年2月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
2,567
试验地点
14
主要终点
Length of Hospital Stay

研究概览

简要总结

Malnutrition in children has even more severe consequences on disease course and long-term health than malnutrition in adults. According to prior studies, malnutrition affects about 15-30 % of hospitalized children in Europe (ESPGHAN 2005, Pawellek et al 2008, Joosten and Hulst 2008). However, available criteria for defining malnutrition in paediatric patients are inconsistent, not based on firm evidence, and not generally agreed upon. Current guidelines do not address assessment of and screening for childhood malnutrition. Therefore, a large number of affected children are not adequately diagnosed.

One aim of this study is to assess the prevalence of malnutrition and patients at risk for malnutrition among at least 2700 hospitalized children mainly across Europe. In addition criteria to link anthropometric measurements and the prediction of outcome, i.e. length of hospital stay, shall be established. A further goal then is to establish agreed, evidence-based criteria for malnutrition in children with the purpose of leading to an agreed, evidence-based screening tool for paediatric malnutrition in developed countries. This tool shall include a set of simple questions, based on previously suggested tools. Thereby this study will provide a strong basis for implementing evidence-based nutritional interventions in paediatric patients by harmonisation of diagnostic criteria for childhood malnutrition in developed countries.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
1 Month 至 18 Years(Child, Adult)
性别
All
接受健康志愿者

入选标准

  • Children admitted to the participating hospitals during the study period
  • Age between 1 month and 18 years
  • Expected hospital stay exceeding 24 hours
  • Parents/caregivers, as well as those patients capable to comprehend, agree to participation and sign the informed consent form

排除标准

  • Infants with premature birth (<37 weeks gestational age) during the first 12 months of life
  • Infants < 1 month of age
  • Patients ≥ 18 years of age
  • Children in need of intensive care
  • Children admitted to day-care (LOS < 24hours)
  • Patients admitted for elective reasons with an expected hospital stay <24 hours

结局指标

主要结局

Length of Hospital Stay

时间窗: 60 days

Length of Hospital Stay will be compared between malnourished and non malnourished children.

次要结局

  • muscle strength(within 24 hours after admission)
  • infection as a complication during hospital stay(60 days)
  • gastrointestinal complications (vomiting, diarrhoea)(60 days)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Koletzko - Office

Prof

Ludwig-Maximilians - University of Munich

研究点 (14)

Loading locations...

相似试验