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临床试验/NCT02846272
NCT02846272招募中不适用

Diffusion Tensor and Functional Connectivity Imaging in Pediatric Epilepsy: Imaging/Histology Correlation

The University of Texas Health Science Center, Houston2 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2015年11月1日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
50
试验地点
2
主要终点
Number of participants with seizure outcome as determined by Engel

研究概览

简要总结

To determine the utility of diffusion tensor magnetic resonance imaging in the preoperative workup of children with intractable epilepsy referred for surgery.

详细描述

To determine if diffusion tensor and functional connectivity magnetic resonance imaging helpful to better understand and diagnose intractable epilepsy in children. All enrolled children will undergo standard preoperative and postoperative MRI imaging, plus a 15 minute set of functional connectivity and diffusion tensor sequence with no additional sedation. This imaging data will be stripped of identifiers and be processed to provide both quantitative analysis, resting state functional connectivity changes and three dimensional modeling of white matter tracts adjacent to epileptogenic foci. This study is being done to determine if diffusion tensor and functional connectivity magnetic resonance imaging are helpful to better understand and diagnose intractable epilepsy in children.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Diagnostic
盲法
None

入排标准

年龄范围
0 Days 至 18 Years(Child, Adult)
性别
All
接受健康志愿者

入选标准

  • Children diagnosis with Intractable Epilepsy

排除标准

  • No Intractable Epilepsy

结局指标

主要结局

Number of participants with seizure outcome as determined by Engel

时间窗: 5 years

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Manish Narendra Shah

M.D. , Assistant Professor

The University of Texas Health Science Center, Houston

研究点 (2)

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