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临床试验/IRCT138903252172N4
IRCT138903252172N4已完成1 期

Effect of valerian root extract on sleep disturbances in menopausal women referred to selected health centers affiliated to Iran University of Medical Sciences 1388

Vice chancellor for reasearch, Iran University of Medical Sciences0 个研究点目标入组 100 人开始时间: 待定最近更新:
适应症

试验速览

阶段
1 期
状态
已完成
发起方
入组人数
100

研究概览

简要总结

Abstract
OBJECTIVE:
Sleep disturbances reduce the quality of life. About 50% of postmenopausal women experience sleep disturbances such as insomnia. Complementary and alternative medical therapies may be useful for the management of sleep disturbances among postmenopausal women. The aim of the present study was to evaluate the effects of valerian extract taken nightly on the improvement of sleep quality in postmenopausal women experiencing insomnia.
METHODS:
A randomized, triple-blind, controlled trial design was used for this study. Participants consisted of 100 postmenopausal women aged 50 to 60 years who were experiencing insomnia. A demographic data form and the Pittsburgh Sleep Quality Index were used to collect data. The women were randomly divided into two groups. Each group received either 530 mg of concentrated valerian extract or a placebo twice a day for 4 weeks. Descriptive and inferential statistics were used to analyze the data.
RESULTS:
A statistically significant change was reported in the quality of sleep of the intervention group in comparison with the placebo group (P < 0.001). Also, 30% of the participants in the intervention group and 4% in the placebo group showed an improvement in the quality of sleep (P < 0.001).
CONCLUSIONS:
Valerian improves the quality of sleep in women with menopause who are experiencing insomnia. Findings from this study add support to the reported effectiveness of valerian in the clinical management of insomnia.

研究设计

研究类型
Interventional

入排标准

年龄范围
50 years 至 60 years(—)
性别
Female

入选标准

  • Inclusion and Exclusion criteria:
  • Not having physical and psychological diseases which may cause sleep problems
  • Not to use tobacco, drugs and alcohol
  • Appearance of any physical illness and psychological disorder while in study
  • Significant change in sleep conditions such as travel, shift work, etc.
  • Taking any additional medication during the study
  • Not taking the drug under investigation for more than 7 days during the study

排除标准

  • 未提供

研究者

发起方
Vice chancellor for reasearch, Iran University of Medical Sciences

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