NCT02934906Unknown不适用
A Multi-center Prospective Cohort Study on the Anti-HPA Antibodies Caused Neonatal Alloimmune Thrombocytopenia in Chinese Pregnant Women
Xinqiao Hospital of Chongqing0 个研究点目标入组 55,497 人开始时间: 2017年1月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 55,497
- 主要终点
- The positive rate of anti-HPA antibody
研究概览
简要总结
This clinical study aims to investigate the anti-HPA antibodies caused neonatal alloimmune thrombocytopenia in Chinese pregnant women. The survey and data collect will help form an appropriate clinical screening procedure
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •12-28 weeks pregnant Chinese women
- •between Jan 1, 2017 and Dec 31, 2018
排除标准
- •Not willing to participate in this study
- •Plan to terminate pregnancy early
结局指标
主要结局
The positive rate of anti-HPA antibody
时间窗: Up to one and a half years after the study completed
The morbidity of NAIT
时间窗: Up to one and a half years after the study completed
次要结局
- Antigenic specificity of anti-HPA antibodies(Up to one and a half years after the study completed)
- The relationship between the titer of anti-HPA antibody and clinical symptom severity in NAIT as assessed by Spearman Correlation assay(Up to one and a half years after the study completed)
- Association of anti-HPA antibody with HLA genotype as assessed by Chi-square test(Up to one and a half years after the study completed)
研究者
Zhongjun Li
Professor, Chief of Blood Transfusion Department
Xinqiao Hospital of Chongqing
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