HFNC Versus Microstream Advance Nasal Cannula for Oxygenation During ERCP
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 74
- 试验地点
- 1
研究概览
简要总结
Endoscopic retrograde cholangiopancreatography (ERCP) procedures are commonly performed under deep sedation and are associated with a risk of hypoxemia, particularly in prone or semi-prone positions. High-flow nasal cannula (HFNC) therapy may improve oxygenation by delivering heated and humidified oxygen at high flow rates, while the Microstream Advance nasal cannula provides simultaneous nasal oxygen delivery and oral oxygen insufflation.
This prospective randomized study aims to compare the effectiveness of HFNC and Microstream Advance nasal cannula in maintaining oxygenation during ERCP procedures. Patients undergoing ERCP will be randomized into two groups receiving either HFNC or Microstream Advance nasal cannula oxygen support during sedation.
The primary outcomes are the incidence of desaturation and oxygen reserve index (ORi) measurements during the procedure. Secondary outcomes include time to achieve target ORi levels, respiratory complications, and procedure-related adverse events.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- None
盲法说明
Due to the nature of the oxygen delivery devices, masking of participants and care providers was not feasible.
入排标准
- 年龄范围
- 18 Years 至 84 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients aged 18 to 84 years
- •ASA physical status I-III
- •Patients scheduled to undergo ERCP
- •Patients who provide written informed consent
排除标准
- •Recent history of upper respiratory tract infection
- •History of lung cancer
- •Chronic obstructive pulmonary disease
- •Body mass index greater than 35 kg/m²
- •Refusal to participate in the study
研究组 & 干预措施
HFNC Group
Participants receive oxygen support with high-flow nasal cannula (HFNC) during ERCP under sedation.
干预措施: High-flow nasal canula (Device)
Microstream Advance Nasal Cannula Group
Participants receive oxygen support with Microstream Advance nasal cannula during ERCP under sedation.
干预措施: Microstream advance nasal cannula (Device)
研究者
Volkan Alparslan
Assistant Professor
Kocaeli University