Subcutaneous Suppressive Antibiotic Therapy for Bone and Joint Infections
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 10
- 试验地点
- 1
- 主要终点
- Description of sub-cutaneous administration of antibiotics for PSAT
研究概览
简要总结
For patients having a bone or joint infections, with or without device, optimal surgical therapy could be sometimes non-feasible, especially in the elderly population. Therefore, a medical therapy with oral prolonged suppressive antibiotic therapy (PSAT) seems to be an option to prevent recurrence and prosthesis loosening.
Subcutaneous (SC) administration of injectable intravenous antibiotics as prolonged suppressive antibiotic therapy could be a convenient way when oral treatment is not available to facilitate ambulatory care, this practice being considered as routine care.
The aim of this study is to evaluate tolerance and efficacy of subcutaneous administration of antibiotics for prolonged suppressive antibiotic therapy in patients having this treatment as part of their routine care.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients having bone or joint infection,
- •patients with or without device treated by sub-cutaneous prolonged antibiotic therapy
排除标准
- •diabetic foot osteomyelitis
- •pressure ulcer-associated osteomyelitis
结局指标
主要结局
Description of sub-cutaneous administration of antibiotics for PSAT
时间窗: 60 months
In case of PSAT (prolonged suppressive antibiotic therapy), the duration could be several years. The data collected are: name of molecule, rough, posology, duration.
次要结局
- Tolerance of sub-cutaneous administration of antibiotics for PSAT(60 months)
- Efficacy of sub-cutaneous administration of antibiotics for PSAT(60 months)